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by arthopacini 11 days ago
for millions of years we were constantly fasting, then we hunted and killed animals, eating their protein and fat, no carbs, we were constantly in ketosis

We recently begun eating carbs, And very very recently started eating tons of processed carbs (because now we got the tech)

We are rarely in ketosis, and because of high carbs/sugar consumption, we start developing insulin resistance. (the idea is simple, we create resistance for most drugs/substances we take, be it anti depressants, caffeine, nicotine and so on.. the same happens with insulin. each time you eat too much sugar, your pancreas needs to issue insulin, so your cells can absorb more sugar. they start being resistant to it, so your pancreas need to work stronger and issue more and more insulin)

insulin is oxidative and inflammatory. we simply weren't built to regulate our blood sugar levels down (we are only equipped with insulin to do so), we are more well equipped to spike glucose levels up (gluconeogenesis, glucagon, cortisol and so on...)

because we are rarely in ketosis, we rarely get into the autophagy state (which is the auto-recycling cell system). so our cells multiply and the most error prone structure is the mitochondria.

mitochondria can make energy either from glucose or fat(keto bodies). it will always prefer glucose, only fallback to keto bodies (fat) when there is no glucose available. the synthesis of ATP (energy) from keto bodies will need oxygen as input, and will yield water as output. if we have inflammation, there is no oxygen (that's why severe chronic inflammation can lead to cancer), also that's why we usually use ice when we hurt ourselves, that place is inflamed, and by putting ice on it, it will change temperature (which changes pressure) and boosts blood circulation, blood carries oxygen, oxygen helps with inflammation.

a cancer cell, with a problematic mitochondria, will not be able to metabolize fat(keto bodies), because it has a problematic carburetor. fact is that the PET scans look for high glucose metabolism places in your body, because the cancer cells are starving for glucose.

the cell DNA is like ECC memory, it has self correction, but the mitochondria lacks the self correction, so it's way simpler to have it gone bad.

every single day we are having tons of cancer cells in our bodies, which self destruct or are detected and destroyed by our immune system.

the Middle East is the region in the world with the least cancer rate in the globe, yet they are one of the top consumers of sugar. but in islam they do the ramadan, in which for one month they make intermittent fasting basically, which boosts autophagy.

anyway... do healthy keto, boost autophagy, avoid ultra processed foods.

actually, I will extend this a little bit more... if you want to enter in keto...

go to the grocery store and buy this:

- meat (ground meat is fine and easy to prepare) - eggs (the most fresh ones if possible) - broccoli - butter or extra virgin olive oil

the portions will depend on your body type and so on.. but you would make meat and eggs on either butter and extra virgin olive oil, salt and pepper, and steamed broccoli. in my case it was 250g of ground meat, 4-5 eggs and one whole broccoli.

you must eat the broccoli first (it's fiber, you can't actually use it, the bacteria in your stomach does, it will make them very happy). if you eat meat+eggs first, you will feel full and will not be able to eat the broccoli, if you eat broccoli first, you will not feel full at all. use salt and pepper and olive oil.

eat the whole broccoli, that's like an ETF of micronutrients, it's very diversified!

then eat eggs+meat no problem...

you gonna feel very very full... do not eat any sugar/carbs.. it can take up to 3 days for entering in ketosis..

you can eat 2 to 3 times a day, eat only when you are genuinely hungry (your hunger will change drastically on how it's built over time)

then slowly entering in ketosis..

the rationale is that you need to cut off the garbage.. meat has high quality protein and fat, so does eggs (an egg has everything needed to begin a freaking life, fun fact: no carbs/sugar in it...)

and the broccoli has micronutrients and make your gut bacteria happy.

the quality of those 3 foods will depend on some things..

for the broccoli, it's the soil... is it contaminated or not? where did it grow?

for the eggs, is the chicken healthy? did she get sun? did she eat insects, worms, or just genetic modified ration?

same for the cattle...

but you are limiting a lot the potential contaminations sources..

4 comments

"for millions of years we were constantly fasting, then we hunted and killed animals, eating their protein and fat, no carbs, we were constantly in ketosis"

Those hunter-gatherers of the past certainly did eat whatever carbs they could find - wild roots, tubers etc. Gathering plant-based food was easier than hunting. Most Westerners today eat way too much meat, so I wouldn't recommend replacing carbs with that.

I agree with a lot here and practice keto throughout the year and occasionally break to eat burritos, rice, pasta and drink beer because I enjoy them. But our ancestors were not in constant ketosis. They ate substantial carbohydrates in the food they consumed seasonally, though not as much as we consume today because of our tech. Also, doesn’t ice reduce blood flow? Lastly Ramadan and cancer rates are not supported. This discounts age distribution, smoking, genetics, environmental exposure, etc.
yeah, I've done keto very strictly for about a year, it solved a major problem in my respiratory system that I had for like.. all of my life

Today I have introduced many carbs back, like sweet potato, cassava, white rice, and fruits etc.. even some orange/grape juice. I just try to stay away from ultra processed foods and occasionally do some fasting.

About our ancestors, I mean... I think it would depend on where in world they were, what was available, and so on... But the majority of fruits didn't existed, and we didn't dominated agriculture and so on... I am not coming from the angle of "we need to go back to eating like our ancestors", but more like in "yeah, they didn't had food all the time, so they kind of were forced into ketosis and autophagy because of fasting"...

I mean, if you do a fast, you know that in like the 24-48 hours window you get a powerful focus, my guess is that the human would focus on hunting. but as you said, we didn't eat too much carbs as today, and the carbs were different as well.. take for example our wheat, it's mainly genetically modified, and so on...

about the ice, yeah.

about the cancer rates, take a look: https://en.wikipedia.org/wiki/List_of_countries_by_cancer_ra...

it's not as easy to say "oh it's ramadan and that's it", but you can clearly see that the Middle East region and africa, which have tons of muslims, have lower cancer rates. intermittent fasting is done in ramadan. it will help with autophagy and health (if done properly).. but I agree that there are tons of other factors as you stated.

and because you cited smoking, I wanna share something. I've recently changed my mind about smoking.

I mean.. those cuban old folks that just chew tobacco all day... they die old. also we never hear about "smoking weed will give you lung cancer"...

that's because smoking tobacco... kind of doesn't give you cancer right away.. I mean, tobacco, specially when cured, will develop carcinogens, sure. but it will be like cooking food in a scratched teflon pan...

it's a plant, like marijuana, but it has been industrialized!

I've said to some people I know that smokes cigarettes: "Go to the tobacconist and buy rolling papers, filters, and shredded natural tobacco."... when they smoke they feel much more of a taste of the tobacco itself, feel it way stronger, and feel an absence of other taste which is only in the industrial cigarette.

idk how to explain cause I don't smoke. but I can only guess that those 9999999 chemicals are just gone... they might be added in the industrial process to further addict people idk..

Without engaging with the rest of your content, I have to point out that Wikipedia's "list of countries by cancer rates" is not actually a useful metric for the true rates of cancer in those countries. Poorer countries tend to have worse medical surveillance and likely undercount. People also die earlier of "other" things than cancer as well.

I understand the desire to make a coherent narrative that fits your beliefs but please recognize the limits in our ability to make causal statements about the causes of cancer.

that was just a quick example. I agree there are tons of noise.

but the biochemistry doesn't change, you just need to see the human system as... a system, like any other system. Yes it will vary depending on genetics, environment and so on, but the base model is still the same.

the system inputs: constant glucose spikes require constant insulin, which drives inflammation and shuts down autophagy, which is bad for cellular and specially mitochondrial repair. what's the output?

also, I don't think it's necessary to mention but... this is not the sole root cause for all cancers in all of history. this is not the "cure". it is not the holy grail... but ask yourself.. what lifestyle are young people having today?

Of course you can make the case that we did consumed some carbs, that eggs actually have a tiny trace of carbs, and get technical on some points...

But the thing is... just restrict potential contaminated food sources.

One example, vegetable oils... God had NO participation in the creation of those.. think about it..

How do you make extra virgem olive oil? you take the olive, then press it.. boom. olive oil..

How do you make avocado oil? Same thing! How do you make cocoa butter? same thing..

Butter is just raw milk shaken, you shake shake shake and you get butter!

These are natural fats.

Now just make a quick google/YouTube search on how is canola/soybean/sunflower/cotton oils made... it's a very complex, multi machinery step, that uses hexane (from crude oil) and other chemicals...

the majority of carbs today are made by processing food. the word (processing) means subtraction, removing things of the food.. they take like a genetically modified corn, process it and then can make some kind of "food", focusing on texture.

because our minds get addicted not only for the taste, but on the texture.. that's what the patents are for...

This is a vibes-based argument, there is no science behind it.

Many traditional foods from around the world have relied on nasty, toxic chemical processes since before chemistry was a real science. If anything, modern understanding of chemistry has made the removal of nasty chemicals much more complete and precise.

dude our soil is contaminated. our food grow from the soil. cattle eat grass that grows from the contaminated soil. be it heavy metals, microplastic, pesticides or other chemicals

for example... corn.. we got genetically modified corn, that grows in contaminated soil... eating corn that is genetically modified is bad, eating corn that is not genetically modified but has grown in contaminated soil is bad, now eating gmo corn that has grown in contaminated soil is super bad.. + pesticides and whatever...

all of this is getting into your body....

if you take animals like cattle and chicken, they are eating grass or insects (actually chickens will eat ration from gmo but ok..)

eating meat from cattle is going to yield less contamination, because it has been filtered by nature (grass) + cattle (liver) and so on... there is a chain of filtering..

if the chicken doesn't get sunlight (vitamin d), the eggs will be depleted of vitamin d, and so on...

I mean, even in fish. it's way safer to eat sardines than big fishes (for mercury buildup for example)

in the 1900s one chicken would took 4-5 months to be ready to be killed.. today it's ready within 5-7 weeks... you can ask old folks how the taste of chicken has changed from when they were young to today...

> dude our soil is contaminated. our food grow from the soil. cattle eat grass that grows from the contaminated soil. be it heavy metals, microplastic, pesticides or other chemicals

That's true but it doesn't mean that the contamination has an actual effect, so vibes. This is not a minor point at all.

> eating meat from cattle is going to yield less contamination, because it has been filtered by nature (grass) + cattle (liver) and so on... there is a chain of filtering..

Assuming your argument of contamination is true does not make this assertion true. Why do you assume their livers do filter things instead of going through bioaccumulation?

> if the chicken doesn't get sunlight (vitamin d), the eggs will be depleted of vitamin d, and so on...

Chickens get supplemented with vitamin D in their feed.

> in the 1900s one chicken would took 4-5 months to be ready to be killed.. today it's ready within 5-7 weeks... you can ask old folks how the taste of chicken has changed from when they were young to today...

This is true. You still need to prove how the dietary profile has changed.

> "That's true but it doesn't mean that the contamination has an actual effect, so vibes. This is not a minor point at all."

If contamination has no effect, why does lard come with a transgenic warning on the packaging? the pig is not genetically modified, but because it consumes gmo food, it's fat becomes contaminated... Why do large fish carry massive, measurable mercury traces? By your logic, you could pour chlorine into a plant's soil, wait a week, and eat it without an issue because "contamination might not have an effect."

> "Why do you assume their livers do filter things instead of going through bioaccumulation?"

Because that is literally what a liver and kidneys do. yours is not the only one that do filter. futhermore, cattle are ruminants, pigs, chickens, and fish are not. they have a completely different digestive system that filters out significantly more toxins before they ever reach the meat, followed by pigs, chickens, and lastly fish.

> "Chickens get supplemented with vitamin D in their feed."

vitamin d supplements are not the same thing as getting direct sunlight. also their food is mainly genetically modified. you know there are different kinds right? cage free, free range and pasture raised. which one do you think has the better nutrient dense meat and eggs quality?

> "This is true. You still need to prove how the dietary profile has changed."

it changed because of synthetic growth hormones, GMO grain feeds, completely different, accelerated industrial breeds and so on..

if you honestly think its "vibes," i highly recommend you test your theory:

1. never ever go outside. stay indoors and only consume vitamin d pills 2 only eat ultra processed, genetically modified foods, and high sugar snacks 3. only use vegetable oils! never ever consume natural oils/fats 4. if you have a garden, pour chlorine on your garden vegetables and eat them a few weeks later. (if they survive it) 5. never fast. eat 6+ times a day to keep your insulin spiked at maximum capacity

> If contamination has no effect, why does lard come with a transgenic warning on the packaging?

In my jurisdiction no such warnings exist. You should check what level of paranoia your region handles because it may be based on evidence or in scaremongering.

> Why do large fish carry massive, measurable mercury traces?

Because large fish are apex predators and apex predators have always had a large amount of contaminants. This holds true now and throughout history, it's not a modern phenomenon.

> By your logic, you could pour chlorine into a plant's soil, wait a week, and eat it without an issue because "contamination might not have an effect."

This is what happens with pesticides, we spray crops and then wait days to weeks for the offgassing or biodegradation. For the record continue to spray crops with water with human and animal feces for nutrition as has been the case throughout human history

> futhermore, cattle are ruminants, pigs, chickens, and fish are not. they have a completely different digestive system that filters out significantly more toxins before they ever reach the meat, followed by pigs, chickens, and lastly fish.

You need to show some evidence of solid studies that show bioaccumulation of toxins because mechanistic effects (or your random theorizing as a layman) are not sufficient proof.

> vitamin d supplements are not the same thing as getting direct sunlight.

You need to show proof of this.

> also their food is mainly genetically modified. you know there are different kinds right? cage free, free range and pasture raised. which one do you think has the better nutrient dense meat and eggs quality?

You need to show proof that the nutrition profile is drastically better. Some free range food tastes different for sure but you need to show me that there's a large enough difference. I am not arguing about the ethics of modern factory farming though.

> 1. never ever go outside. stay indoors and only consume vitamin d pills 2 only eat ultra processed, genetically modified foods, and high sugar snacks 3. only use vegetable oils! never ever consume natural oils/fats 4. if you have a garden, pour chlorine on your garden vegetables and eat them a few weeks later. (if they survive it) 5. never fast. eat 6+ times a day to keep your insulin spiked at maximum capacity

I mean hundreds of millions of people do this and most of these things have been studied, quite literally to death.

* We know the effects of vitamin D supplementation (favorable compared to more than moderate sun exposure as direct sun exposure brings risks of melanoma)

* We know the effects of GMO: no known effects at all, no specific mechanism of action of because GMO is meaningless unless you can tell me of specific genetic changes that trigger the creation of some toxin in the target organism

* We know the effects of ultraprocessed foods: largely attributable to high palatability that leads of greater body mass and spikes in glycemic index if not supplemented with fiber or physical activity.

* There have been hundreds of studies on vegetable oils and not a single one has shown negative effects beyond what you might get from excess calories. Have you actually read these studies? You talk about "natural" oils, which is a completely meaningless term.

* The garden thing is a stupid analogy and dependent on the chemistry of whatever chemical in question you're talking about. You know that chemistry is an exact science and we can know empirically how different substances biodegrade right?

* Fasting has some marginal health benefits but is ultimately just a method of calorie restriction, which is healthy overall. No human randomized control trial has shown fasting to be better than alternative methods of dieting.

* Likewise, the number of times you eat does not have and known impact when you equate for calories.

Wrong about olive oil that never need hexane extraction. Hexane is used to do a second extraction of the residues from the first extraction, to increase the yield. Of course it is somewhat poisonous. It is done for most cheap olive oil ! When buying olive oil, you have to make sure it is extracted mechanically and not chemically, in France at least it is written as such.
I've never encountered chemically extracted olive oil, thanks god! I didn't knew they used it. it makes sense, just to increase the yield..

I've only seen mechanically extracted extra virgem olive oil.

I've seen some mixtures of like 80% vegetable oils with 20% natural extra virgin olive oil..

also like obese young children... how is this even possible? this is very recent... so yeah.. they did sabotage our food.

if you think about the human being a black box, and food (macro nutrients, fiber, carbs, protein and fat) being inputs, you could test it and find how to break the system, make it weak, obedient and addicted...

Yes.

Also:

Look at where the “fat” is being stored.

Realize it’s not all “fat” from calories - it’s inflammation, and toxin diversion.

Fat doesn’t get stored in your eyebrows in front of your sinus,

that’s swelling from eating what the body sees as toxic,

and often breathing poison indoors.

that makes total sense! it can get in a state where the body really need to freaking store the fat somewhere else and/or even the toxins because it is unable to get rid of it...
What goes in has to go somewhere.

We think we can always break down, or excrete, 100% of what we ingest, inhale.

We are wrong.