[mistermann]

> It takes a long pause from stress for you mind and body to stop over-producing stress hormones.

I can vouch for this, I feel like I have been permanently damaged from a multi-year stressful job.

Speaking of stress hormones, does anyone in this thread know if there's some quantitative way to measure stress hormone levels, even if it's only somewhat accurate?

The best real relief I've managed to find is microdosing psilocybin combined with meditation, this seems to allow me to see right through my negative beliefs & perceptions, but also largely eliminate the ongoing ~unavoidable mental/emotional (eventually manifesting in physical) reactions to them. It feels like it allows me to mostly not give a fuck about things like normal people. Perhaps something the grandparent should look into.

[blackflame7000]

Yes, stress levels are tied to cortisol levels in the bloodstream. This is especially bad for your physical health as it will cause you to store fat and crave sugary foods. The single best thing you can do is exercise 5 times a week for at least 45 minutes. It will retrain your brain to embrace stress because of the endorphin reward you get after. I promise you, the gym is never as hard as people make it out to be in their mind. 90% is just showing up. Don't take shrooms, you're just messing up your brain chemistry even more with a temporary bandaid. Furthermore, you're treating yourself with a drugs side-effect. If anything the drug you are looking for is Ativan or Xanax. I'm someone who used to be majorly overweight, overworked and stressed to no end, but exercise changed my life.

[sharadov]

I totally agree, too little is known about drugs and how they react with each individual's bio- chemistry. Exercise in any form can only be beneficial, I've been through some really stressful periods and nothing like it ( if you can play a sport even better..it will give you a sense of accomplishment that is probably missing from your job). Eat healthy , have someone who can listen to you and support you. And have a plan to get out, could be a year out , but it will give you a sense of purpose.

[o-__-o]

>If anything the drug you are looking for is Ativan or Xanax

be very careful, these drugs don't fix the problem but rather solve panic attack type situations. if you can breathe, you do not need these medicines. there are lots of other medicines that are not benzos that treat the anxiety at the source.

i am speaking from experience, i was taking ativan "as needed" and ended up in an overnight psych hold as my stress outbursts kept getting worse until my family feared for my safety. stopped all medication for a month, switched to an anti-depressant to sleep temporarily, switched to less agitated medicine, 10 months later i feel like i'm on top of the world and have started taking back ownership of activities in my business.

ativan and xanax wont' stop the stress, it masks it.

[throwawayxyz51c]

> If anything the drug you are looking for is Ativan or Xanax.

No it really isn't, even if it might seem that way in the short term.

Source: Personal. Xanax for occasional stress turned into Xanax for sleep sometimes turned into Xanax every night or insomnia. Kicking the habit now and it really sucks.

Stick to exercise and meditation. Actually agree with grandparent about the benefits of psilocybin, but you probably shouldn't listen to a stranger on the internet about that anyway.

Throwaway for obvious reasons.

[throwaway344534]

https://pbs.twimg.com/profile_images/378800000485764460/e2e5...

[mistermann]

Not that you and I disagree, but some important additional details on the matter:

> Actually agree with grandparent about the benefits of psilocybin, but you probably shouldn't listen to a stranger on the internet about that anyway.

You certainly shouldn't base your opinion on one comment on the internet. What you should do they is consider it a possibility and do your own research, at which time you will discover there is significant discussion on the internet among both layman and professionals about not just the observed benefits (sometimes bordering on the profoundly amazing [1]), but also increasing detailed, science-based theories about the underlying physiological and neurological causes for the observed successes.

You will also realize the ratio of successful outcomes to unsuccessful (no result or harmful) are heavily skewed towards successful stories. Is this ratio driven by a bunch of drug-addled delusional lunatics, or might there be something interesting going on here?

[1] https://www.newyorker.com/magazine/2015/02/09/trip-treatment

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As I chatted with Tony Bossis and Stephen Ross in the treatment room at N.Y.U., their excitement about the results was evident. According to Ross, cancer patients receiving just a single dose of psilocybin experienced immediate and dramatic reductions in anxiety and depression, improvements that were sustained for at least six months. The data are still being analyzed and have not yet been submitted to a journal for peer review, but the researchers expect to publish later this year.

“I thought the first ten or twenty people were plants—that they must be faking it,” Ross told me. “They were saying things like ‘I understand love is the most powerful force on the planet,’ or ‘I had an encounter with my cancer, this black cloud of smoke.’ People who had been palpably scared of death—they lost their fear. The fact that a drug given once can have such an effect for so long is an unprecedented finding. We have never had anything like it in the psychiatric field.”

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"But this can't possibly be true", one might semi-reasonably propose, "because if it was we would surely know about it!"

Incorrect. That is an logical/epistemic error, something that is at the foundation of a large portion of any common disagreement in society, from politics to finance to personal relationships.

As the saying goes: "It Ain’t What You Don’t Know That Gets You Into Trouble. It’s What You Know for Sure That Just Ain’t So"."

One reason "because if it was we would surely know about it" should not be taken for granted is in the same article:

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“I felt a little like an archeologist unearthing a completely buried body of knowledge,” he said. Beginning in the nineteen-fifties, psychedelics had been used to treat a wide variety of conditions, including alcoholism and end-of-life anxiety. The American Psychiatric Association held meetings centered on LSD. “Some of the best minds in psychiatry had seriously studied these compounds in therapeutic models, with government funding,” Ross said.

Between 1953 and 1973, the federal government spent four million dollars to fund a hundred and sixteen studies of LSD, involving more than seventeen hundred subjects. (These figures don’t include classified research.) Through the mid-nineteen-sixties, psilocybin and LSD were legal and remarkably easy to obtain. Sandoz, the Swiss chemical company where, in 1938, Albert Hofmann first synthesized LSD, gave away large quantities of Delysid—LSD—to any researcher who requested it, in the hope that someone would discover a marketable application. Psychedelics were tested on alcoholics, people struggling with obsessive-compulsive disorder, depressives, autistic children, schizophrenics, terminal cancer patients, and convicts, as well as on perfectly healthy artists and scientists (to study creativity) and divinity students (to study spirituality). The results reported were frequently positive. But many of the studies were, by modern standards, poorly designed and seldom well controlled, if at all. When there were controls, it was difficult to blind the researchers—that is, hide from them which volunteers had taken the actual drug. (This remains a problem.)

By the mid-nineteen-sixties, LSD had escaped from the laboratory and swept through the counterculture. In 1970, Richard Nixon signed the Controlled Substances Act and put most psychedelics on Schedule 1, prohibiting their use for any purpose. Research soon came to a halt, and what had been learned was all but erased from the field of psychiatry. “By the time I got to medical school, no one even talked about it,” Ross said.

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[mistermann]

Thanks for the advice.

And not to be argumentative, but I think it's fair to say that neither you nor anyone else on the planet knows with certainty the full range of possible benefits and detriments to exercise, psilocybin (particularly, in no small part because it is illegal to even formally study for the most part), or anything else for that matter.

[blackflame7000]

Human's might not have a full understanding but there's an entire branch of science (pharmacology) dedicated to studying these things. We know that Alcohol has a detrimental effect on your coordination just like we know Psilocybin has a detrimental effect on your perception of reality. Frankly, I think it's far less strange for someone to show up to work high than tripping.

[mistermann]

> We know that Alcohol has a detrimental effect on your coordination just like we know Psilocybin has a detrimental effect on your perception of reality

Incorrect. We do not in fact know that "Psilocybin has a detrimental effect on your perception of reality", as an absolute. This could be said about many scenarios, maybe even most, but the statement at face value implies there are no beneficial effects on perception of reality, in any scenario. Any such claim is flawed both logically and epistemically.