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by cwisecarver 3315 days ago
Related: https://www.elysiumhealth.com

I've been taking this for about 6 months. Haven't noticed much other than better sleep, easier to wake upon time feeling refreshed.
1 comments
mkempe 3315 days ago
That's NR, not NMN. Also, the daily Elysium dose of NR is 500mg, much less in proportion to body weight than what was fed to the mice in this Harvard study.

Added: Thanks to jclos below. The human-mouse-equivalent NMN dose would be 1/12th, 25mg/kg of bodyweight/day.

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jclos 3315 days ago
Keep in mind that there is no 1:1 mapping between mg/kg/day for mice and for humans due to difference in metabolism. http://www.ergo-log.com/calculatethehumandosage.html gives a couple of useful formulas to calculate the actual dosage for humans and it's much more reasonable.
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TrainedMonkey 3315 days ago
Having done some ECLSS stuff it takes about 13 mice to equal metabolic load of a human. This does not add up if you use mass alone, but comes out pretty close using volume/surface area metric.
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cwisecarver 3315 days ago
It does boost production of NDA+ though, right?
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mkempe 3315 days ago
Yes, but the dose must be important. Brenner [1] took 1g NR/day for 7 days during his self-study.

[1] https://medcom.uiowa.edu/theloop/news/first-human-clinical-t...

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