[mkempe]

That's NR, not NMN. Also, the daily Elysium dose of NR is 500mg, much less in proportion to body weight than what was fed to the mice in this Harvard study.

Added: Thanks to jclos below. The human-mouse-equivalent NMN dose would be 1/12th, 25mg/kg of bodyweight/day.

[jclos]

Keep in mind that there is no 1:1 mapping between mg/kg/day for mice and for humans due to difference in metabolism. http://www.ergo-log.com/calculatethehumandosage.html gives a couple of useful formulas to calculate the actual dosage for humans and it's much more reasonable.

[TrainedMonkey]

Having done some ECLSS stuff it takes about 13 mice to equal metabolic load of a human. This does not add up if you use mass alone, but comes out pretty close using volume/surface area metric.

[cwisecarver]

It does boost production of NDA+ though, right?

[mkempe]

Yes, but the dose must be important. Brenner [1] took 1g NR/day for 7 days during his self-study.

[1] https://medcom.uiowa.edu/theloop/news/first-human-clinical-t...