[jclos]

Keep in mind that there is no 1:1 mapping between mg/kg/day for mice and for humans due to difference in metabolism. http://www.ergo-log.com/calculatethehumandosage.html gives a couple of useful formulas to calculate the actual dosage for humans and it's much more reasonable.

[TrainedMonkey]

Having done some ECLSS stuff it takes about 13 mice to equal metabolic load of a human. This does not add up if you use mass alone, but comes out pretty close using volume/surface area metric.