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1.
CRISPR tech selectively shreds cancer cells, including "undruggable" cancers (innovativegenomics.org)
438 points by gmays 4 hours ago | 117 comments
2.
I Am Not a Reverse Centaur (blog.miguelgrinberg.com)
137 points by ibobev 2 hours ago | 96 comments
3.
How to setup a local coding agent on macOS (ikyle.me)
100 points by kkm 2 hours ago | 35 comments
4.
Malware developers added nuclear and biological weapons text to to their spyware (twitter.com)
152 points by marc__1 23 hours ago | 96 comments
5.
Pirates, a naval warfare game inspired by Sid Meier's Pirates (piwodlaiwo.github.io)
80 points by iweczek 3 hours ago | 32 comments
6.
Looking Forward to Postgres 19: It's About Time (pgedge.com)
87 points by xngbuilds 3 hours ago | 24 comments
7.
A PDF that changes based on how its read (sgaud.com)
79 points by SarthakGaud 3 hours ago | 42 comments
8.
Slightly reducing the sloppiness of AI generated front end (envs.net)
127 points by FergusArgyll 5 hours ago | 82 comments
9.
Law Enforcement's "Warrior" Problem (2015) (harvardlawreview.org)
46 points by bookofjoe 3 hours ago | 37 comments
10.
A dumpster arrived behind my university's library (yalereview.org)
128 points by mooreds 5 hours ago | 104 comments
11.
Launch HN: BitBoard (YC P25) – Analytics Workspace for Agents (bitboard.work)
19 points by arcb 3 hours ago | 8 comments
12.
Where Did Earth Get Its Oceans? Maybe It Made Them Itself (quantamagazine.org)
75 points by ibobev 4 hours ago | 45 comments
13.
AI agent bankrupted their operator while trying to scan DN42 (lantian.pub)
1337 points by xiaoyu2006 15 hours ago | 481 comments
14.
There Is Life Before Main in Rust (grack.com)
42 points by mmastrac 1 day ago | 12 comments
15.
Introduction to UEFI HTTP(s) Boot with QEMU/OVMF (blog.yadutaf.fr)
44 points by jtlebigot 5 hours ago | 12 comments
16.
Maxproof (arxiv.org)
117 points by ilreb 8 hours ago | 9 comments
17.
Cosmodial Sky Atlas (killedbyapixel.github.io)
13 points by memalign 1 hour ago | 1 comments
18.
"Don't You Just Upload It to ChatGPT?" (correresmidestino.com)
117 points by speckx 2 hours ago | 110 comments
19.
A Call to Action: Stop the FCC's KYC Regime (blog.lopp.net)
278 points by FergusArgyll 5 hours ago | 181 comments
20.
Hazel (YC W24) Is Hiring a Full Stack Engineer (ycombinator.com)
1 points by augustschen 6 hours ago
21.
If you are asking for human attention, demonstrate human effort (tombedor.dev)
1405 points by jjfoooo4 21 hours ago | 442 comments
22.
WASI 0.3 (bytecodealliance.org)
202 points by mavdol04 6 hours ago | 82 comments
23.
Show HN: StackScope – I crawled over 40k indie launches to see what they ship (stackscope.dev)
29 points by datafreak_ 4 hours ago | 8 comments
24.
How we made hit video game Prince of Persia (theguardian.com)
252 points by msephton 2 days ago | 103 comments
25.
New privacy frontier: Europe eyes crackdown on smart glasses (politico.com)
61 points by 1vuio0pswjnm7 3 hours ago | 44 comments
26.
Encrypted Spaces An architecture for collaborative applications (encryptedspaces.org)
49 points by _____k 7 hours ago | 5 comments
27.
Kimi K2.7-Code: open-source coding model with better token efficiency (huggingface.co)
354 points by nekofneko 9 hours ago | 193 comments
28.
A jacket that harvests drinking water from the air (news.utexas.edu)
146 points by ilreb 21 hours ago | 92 comments
29.
Show HN: Script to bulk delete Claude chats from the web UI (github.com)
45 points by ML0037 5 hours ago | 16 comments