[WarDekar]

No hangover? Except for, let's see, a short list:

Severely depleted serotonin levels, causing irritability and possibly depression

Loss of focus, concentration, and attention (good luck programming competently the day after)

Bruxism (jaw clenching/grinding)

[cnp]

Hangovers tend to occur when you've had MDMA mixed with one of the ever-more-frequent mixers such as methamphetamine, cocaine or even MDA, which actually targets dopamine receptors far more prominently than the serotonin and knock you out for days. Pressed pills are usually the culprit, and I would avoid them unless you know exactly where they're coming from.

From a wide array of experience, pure MDMA (in recommended doses, meaning 200mg or less) produces less of a hangover than two beers, with a very real "afterglow" which lasts for days after. Excellent focus and concentration included.

This is a good read: http://www.cbc.ca/news/canada/british-columbia/pure-ecstasy-...

[WarDekar]

From your own article:

"The drug's letdown can include feelings of confusion, irritability, anxiety, paranoia and depression, and people may experience memory loss or sleep problems, jaundice or liver damage."

And:

"Dr. John Halpern, a Harvard Medical School assistant professor who led the research, said pure MDMA can change core body temperature, heart rate and blood pressure in the short-term, and decrease immune resistance for a few days."

Sounds like a hangover to me:

"2a : disagreeable physical effects following heavy consumption of alcohol or the use of drugs" http://www.merriam-webster.com/dictionary/hangover

I'm not saying MDMA is terrible for you, but it certainly does cause hangover effects (and of course, this will vary by person).

[berberous]

It definitely varies by person. I know people who say they consistently get an afterglow and feel even better the next day, whereas others consistently feel the serotonin deficiency and can feel a bit depressed. The jaw clenching seems to be more universal.

[thatswrong0]

There are also supplements that help prevent the negative side effects plus protect against some of the toxicity.. magnesium + gum for the jaw clenching, Vitamin C [1][2] + ALA [3] + Vitamin E [4] + others for antioxidants and preventing neurotoxicity and hepatoxicity.

1: http://www.ncbi.nlm.nih.gov/pubmed/15212815 2: http://onlinelibrary.wiley.com/doi/10.1002/1098-2396%2820010... 3: http://www.ncbi.nlm.nih.gov/pubmed/10619665 4: http://www.ncbi.nlm.nih.gov/pubmed/11931860

[davvid]

Bruxism (jaw clenching/grinding)

This happens when MDMA is cut with meth. I think he mentioned "pure", but when it's illegal it's hard to guarantee purity, so legalization would have at least that benefit.

[llllllllllll]

I'm pretty sure that jaw clenching happens with pure MDMA. I've experienced it on every roll, with stuff sourced from a variety of highly rated Silk Road vendors.