You need a little more than familiarity with programming to get started with a JS toolkit.
Most JS toolkits are heavily biased towards the browser environment, so you also need some knowledge of the DOM and the host environment provided by browsers for JS execution.
http://ajax.googleapis.com/ajax/libs/jquery/1.3.2/jquery.js
Be patient and focus on understanding one part that your are familiar with - perhaps handling AJAX requests.