| It only reduces by 4 events per hour. That seems like it might be helpful for someone with mild sleep apnea. But not with moderate or severe sleep apnea. Adult AHI Severity Levels Normal: Less than (5) events per hour. Mild Sleep Apnea: (5) to (14.9) events per hour (frequent minor interruptions). Moderate Sleep Apnea: (15) to (29.9) events per hour.Severe Sleep Apnea: (30) or more events per hour. "By mapping the neural circuits that lead to this common condition, work from the Horner lab laid the foundation for AD109, a new treatment developed by researchers in Boston to specifically target the two pathways that contribute to sleep apnea. The daily oral medication contains two drugs: one that increases noradrenaline levels and another that blocks muscarinic receptors. In a recently published phase 3 randomized clinical trial, people with mild to severe sleep apnea who received AD109 had less airway obstruction and higher oxygen levels than those who received a placebo. On average, per hour of sleep, participants on AD109 had four fewer events where they stopped breathing or had very shallow breathing." |