[eftpotrm]

And yet it happens. A doctor in my family told the story of a patient they were treating in hospital who medically needed to lose weight, and who they found unable to get any reduction until they dropped below _200_ calories a day.

Metabolism is _significantly_ more complex than CI/CO, from experience.

[nom]

What is more likely:

- a physics-breaking thermodynamic anomaly

- a food addicted person is lying about their consumption

200 kcal a day.. yeah sure. A human body needs more than that just to breathe and pump blood. Even comatose a skinny person needs 5 times as much.

Overweight people have a significantly higher metabolic base rate. Just breathing can easily be 1000kcal a day if your lungs have to move 30 kilos of upper body fat 10 times a minute. They also have more muscle mass compared to the average person their size, even when not physically active, which increases MBR as well.

Weight loss and gain is a solved problem, but self control and human behavior is not.

Perpetuating myths of impossible weight loss is not beneficial for our society and moves us further away from solving the underlying issues.

[iteria]

I can believe this as a human who fasts. I just don't eat every other day. I've fasted for multiple days. You would amazed at how much the scale doesn't move. I can lose zero weight after 36 hours of nothing but water entering me. The body is less CICO and more a system trying to maintain homeostasis as much as possible and pulling ever lever it can.

Yes, eventually eating every other day I did lose weight, but we're talking a steady glide of 1-2lbs a week nothing as severe as people would expect a severely overweight person who only ate half the week to lose.

[raincom]

If you treat humans as biological machines, signaling system (hormones, endocrine system) is very important. When signaling system is messed up, your CI/CO model with self-control doesn't work at all. Signals need to be fixed.

[tekla]

So? That doesn't disprove the premise of CI/CO. CI/CO is the notion that humans exist in the physical world and thus obey the laws of thermodynamics.

[raincom]

CI + self-control or will --> CO (that's the hypothesis sold by many)

CI + hormones --> CO (that's an alternative hypothesis)

[yakz]

> Weight loss and gain is a solved problem, but self control and human behavior is not.

Semaglutide and tirzepatide address the self control and human behavior problems. They stop you from wanting to eat more.

[djmips]

https://www.diabetes.co.uk/blog/2018/02/story-angus-barbieri...

[guerrilla]

It's insane how arrogant people can be about this. You have not accounted for all of the variables and that is blatantly obvious. The phenomenon is well known and there are multi-variable equations for it, many different models. One popular model is that NEET can decrease below the caloric deficit, meaning you still gain weight by becoming subconsciously lazier despite everything feeling equally difficult subjectively. There are several other more advanced models adding other variables, some depending on insulin sensitivity, for example. Anyway, no physics is broken, laymen are just naive to the complexity abd adaptability of biology.

[_Algernon_]

200kcal/day is less than 10W. Since all energy the body uses is released as heat this puts the maximum sustainable heat radiation with such a diet at 10W.

That's about the level of a typical household LED, which at most feels slightly warm to the touch.

At that energy level you could not sustain weight while maintaining body temperature let alone having a healthy metabolism. That's just a plain fact.

You will lose weight long before you reach 200kcal/day.

[guerrilla]

That's a good argument against what I said for this particular case. I didn't realize 200kcal was so little. Imagine my comment was written in reply to a higher number though because that criticism is definitely valid for a large number of posts people make in general. ;)

[krageon]

But it is basic physics, which is in fact being violated. It's really very normal to require exceptional proof for this. Like literally any scientific study, not just an anecdote claiming magic.

[stonemetal12]

Basic physics says CI/CO applies to a closed system. Show me a closed system human and then it will be applicable.

E=MC^2 is basic physics too. So eat a pea and have enough calories for the rest of your life and then some?

[krageon]

You are implying that humans receive energy from another source, which is an extraordinary claim that you should motivate somehow.

[bluecheese452]

It is the amazing the hoops people will jump through and the lies they will tell themselves and others rather than facing the obvious truth that they are consuming too many calories.

[karn97]

Nutritional science is pseudo science at best. I had rather continue to believe in thermodynamics lmao

[_Algernon_]

You cant cheat thermodynamics, so something does not add up. Most likely the calorie estimates if they were self reported.

To illustrate a single 37.5g snickers is slightly below 200kcal. I probably get that number of calories just from the milk in my coffee in an average day.

[throwaway2037]

Whole milk (3.25% fat) is ~60kcals per 100grams. Are you really drinking 300+grams of whole milk in your coffee per day?

[ykonstant]

For how long? Irregularities can persist for a small amount of time, no doubt; but for how long does one maintain weight and life on 300 calories a day?

[bowsamic]

1000 calories is already an unbelievable claim, absolutely no one is going to believe 200. That’s just absurd

[phyalow]

Come on, this is ridiculous.

CI/CO is a thing.

https://en.m.wikipedia.org/wiki/Thermodynamics

[inglor_cz]

I don't believe that people can gain weight while eating almost nothing, but I believe that their internal distribution of energy may be out of whack.

Proponents of naive thermodynamics model tend to assume that only "excessive" energy is stored into bodily fat, once all the other tissues have had their fair share.

That is not really true in insulin resistant people, whose storage may be excessive and leave the rest of the body unsatisfied and hungry, which drives them to eat more than a healthy person would.

To us, this looks like deliberate overeating, to them, it is a result of constant hunger caused by the fact that some part of the energy consumed is being immediately locked away in fat tissues by dysregulated metabolic processes.

Notably, it isn't easy to "correct" this situation by just eating less, because that will leave those people feeling really starved. Insulin sensitivity must be restored first, then the fat stores will give up their excess willingly and that person won't suffer.

[d4704]

Agreeing and I found it interesting to learn more about caloric availability to the body.

I.e. calories on the label vs what the body can actually access.

Like drinking smoothies (high availability) vs raw fruit (lower availability)

Dr. Greger (Nutrition focused) discusses some of this on calorie density and some referenced studies here if interested:

https://nutritionfacts.org/blog/how-to-lose-weight-eating-mo...