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by LinuxBender 444 days ago
Instead of learning software engineering I would want to learn:

Chemically induced reprogramming to reverse cellular aging [1] a.k.a. OSKM

My first experiments would be on some really old horses. I could probably buy a 30 year old horse from a neighbor. She is on her last leg. I want to make her younger again and then just let her have many more years of chilling and not having to make babies every year. If can learn this well enough to reverse the age of a dozen horses then my second test subject would be myself. If I get that right then my friends could optionally do the same.

[1] - https://www.aging-us.com/article/204896/text

1 comments

This is not meant to be snarky, but I can't help but ask:

* Did I miss a tone indicator (/s) in your response?

* If not, why do you think that transcriptional reprogramming of fibroblast cells in culture (as per the Yang et al. paper you cite), which results in "reversing trancriptomic age" can be applied to whole organisms?

* Ignoring the "de-aging" horses bit, is it realistic to think that getting a handle on the science behind cellular reprogramming is really just a 100 hour task?

can be applied to whole organisms?

Because it has been for several years in mice and monkeys.

really just a 100 hour task?

To learn, yes. It is a well established process. Mice have been aged, de-aged, aged, de-aged using this process. One can find videos on Youtube from Dr. Sinclairs team that show the mice and their physical abilities during the entire process. This has also been used on humans specifically in the optic nerves but it won't be long before it is approved for body-wide usage. I would not expect the learning process to exceed 72 hours not counting breaks.