[LinuxBender]

can be applied to whole organisms?

Because it has been for several years in mice and monkeys.

really just a 100 hour task?

To learn, yes. It is a well established process. Mice have been aged, de-aged, aged, de-aged using this process. One can find videos on Youtube from Dr. Sinclairs team that show the mice and their physical abilities during the entire process. This has also been used on humans specifically in the optic nerves but it won't be long before it is approved for body-wide usage. I would not expect the learning process to exceed 72 hours not counting breaks.