It's not a miracle drug. Check this Joe Rogan interview to understand at a deep level all the problems with a drug like Ozempic: https://www.youtube.com/watch?v=G0lTyhvOeJs
I know this going to be blasfemy but the real problem here is carb addiction and we should be treating the root cause not the symptoms with a drug with unpredictable long term consequences.
I'd second this opinion – weight can be lost so easily by dropping the majority of carbs. By that I mean base one's nutrition on meat / fish / eggs / vegetables / fruit, with no pasta, no bread, no sweets, no cake, no chips/crisps, no biscuits / cookies etc (and no booze too, or at least keeping it very minimal or sporadic).
If you do 1000+ calories a day of exercise above your basic metabolic rate / consumption, you will lose 1kg/2lb per week. I'm doing this at the moment (and then will be continuing beyond) and it really does work. I do, however, have the luxury of spending 3-5 hours a day in the gym & fitness classes and swimming pool, and cycle there and back. My Apple Watch is amazing at tracking the calories burned in all these exercises, so I know that I'm burning 3500 - 4800 calories a day from exercise. It's trivial to then only eat around 2000-2500 calories a day. This can barely even be classified as a diet, just healthy choices.
The availability of cheap calories and easy carbs everywhere really is the peril of the western diet. Eating vegetables and protein is a little strange at first but the weight will drop off without having to feel hungry. Hence I'll be joining you in the blasphemy, but this really is a solution to excess weight and it's simple maths that cannot be cheated by the body – unless one has some kind of extreme medical condition, the body simply will not stay heavy while running a deficit and a high protein and low "lazy" carb diet. And I'm saying this as someone who has a decent amount invested in both Novo Nordisk and Eli Lily stocks...
Yet it seems that now these drugs exist, it's easier and quicker to take them as a fast track, because if you're 50kg / 100lb overweight, then to say to someone "you need to exercise quite a lot every day, while not eating cheap carbs, for a whole year and then continue beyond" it simply seems too difficult and hard.
I would listen to what his guests on this particular podcast have to say before jumping into conclusions just because the interviewer is Joe Rogan.
I have no particular opinion on him - I’m just interested in what the interviewees in this specific episode have to say about metabolic health which has direct implications on the massive usage of drugs like ozempic.
I'll start with stating that Joe Rogan has, as the years have gone on, resulted to more and more fringe guests on basically every subject.
Then I'll point out that these guests are MDs, not PhDs.
And then I'll point out this bit from the description:
> Dr. Casey Means is the Co-Founder of Levels Health, which provides insights into metabolic health through real-time data. Calley Means is the Co-Founder of Truemed, which enables HSA spending on healthy food, supplements and exercise. They are the co-authors of "Good Energy."
Their livelihood is based on selling people apps, services, hardware, supplements, etc. around a certain lifestyle. They've got direct financial incentive to be against GLP1 medications.
For any specific claims, well, if you're going to use a video for reference, present the specific claims, timestamps, etc. You can't expect random people on the internet to watch a two and a half hour video off of nothing more than "you'll understand at a deep level the problem with glp1 drugs!"
In contrast with the huge amount of money that the pharma industry spends in marketing GLP1 drugs to people not caring about their long term effects but only on profit.
I wish there were more Casey and Calley Means in this world instead of ever more metabolic and mentally ill society living more like zombies than free human beings.
> In contrast with the huge amount of money that the pharma industry spends in marketing GLP1 drugs to people
Drugs lose their patents and much of the research on novel medications is done in partnerships with universities, etc. Plenty of other scientists unrelated to the drug companies are continuing research through entirely separate funding. But I guess everyone is in the pocket of big pharma?
> not caring about their long term effects but only on profit.
What long term effects? You still haven't elucidated any concerns.
> I wish there were more Casey and Calley Means in this world instead of ever more metabolic and mentally ill society living more like zombies than free human beings.
You can find plenty of them on instagram, youtube, and tiktok. They'll be happy to sell you another fitness device and Yet Another Protein Powder or a pill made out of some plant extract that has minimal to no scientific evidence of efficacy.
Every drug has long term side effects but people are being sold GLP1 as a miracle weight lost pill when the focus should be on reducing all the toxic junk food that is causing the weight gain in the first place.
And yes, many research programs are funded by pharma - the conlict of interests is blatant and getting more people sicker every year.
Honestly, I’m pretty sure you’re very aware of all this so I question your motivations to be openly promoting a drug that interferes directly with cellular metabolism like if you’re selling candy.