[arijo]

I would listen to what his guests on this particular podcast have to say before jumping into conclusions just because the interviewer is Joe Rogan.

I have no particular opinion on him - I’m just interested in what the interviewees in this specific episode have to say about metabolic health which has direct implications on the massive usage of drugs like ozempic.

[cthalupa]

I'll start with stating that Joe Rogan has, as the years have gone on, resulted to more and more fringe guests on basically every subject.

Then I'll point out that these guests are MDs, not PhDs.

And then I'll point out this bit from the description:

> Dr. Casey Means is the Co-Founder of Levels Health, which provides insights into metabolic health through real-time data. Calley Means is the Co-Founder of Truemed, which enables HSA spending on healthy food, supplements and exercise. They are the co-authors of "Good Energy."

Their livelihood is based on selling people apps, services, hardware, supplements, etc. around a certain lifestyle. They've got direct financial incentive to be against GLP1 medications.

For any specific claims, well, if you're going to use a video for reference, present the specific claims, timestamps, etc. You can't expect random people on the internet to watch a two and a half hour video off of nothing more than "you'll understand at a deep level the problem with glp1 drugs!"

[arijo]

In contrast with the huge amount of money that the pharma industry spends in marketing GLP1 drugs to people not caring about their long term effects but only on profit.

I wish there were more Casey and Calley Means in this world instead of ever more metabolic and mentally ill society living more like zombies than free human beings.

[cthalupa]

> In contrast with the huge amount of money that the pharma industry spends in marketing GLP1 drugs to people

Drugs lose their patents and much of the research on novel medications is done in partnerships with universities, etc. Plenty of other scientists unrelated to the drug companies are continuing research through entirely separate funding. But I guess everyone is in the pocket of big pharma?

> not caring about their long term effects but only on profit.

What long term effects? You still haven't elucidated any concerns.

> I wish there were more Casey and Calley Means in this world instead of ever more metabolic and mentally ill society living more like zombies than free human beings.

You can find plenty of them on instagram, youtube, and tiktok. They'll be happy to sell you another fitness device and Yet Another Protein Powder or a pill made out of some plant extract that has minimal to no scientific evidence of efficacy.

[arijo]

Every drug has long term side effects but people are being sold GLP1 as a miracle weight lost pill when the focus should be on reducing all the toxic junk food that is causing the weight gain in the first place.

And yes, many research programs are funded by pharma - the conlict of interests is blatant and getting more people sicker every year.

Honestly, I’m pretty sure you’re very aware of all this so I question your motivations to be openly promoting a drug that interferes directly with cellular metabolism like if you’re selling candy.

[cthalupa]

You're still not providing any sort of claim as to what actual negative side effects you are concerned about, so I don't really know how to have a serious conversation with you.

"Interfering with cellular metabolism" is a meaningless phrase. Please provide some sort of method of action that you are actually concerned about. What is it that it is doing to cells that we should be concerned about? What scientific evidence is there that this action is unhealthy?

[arijo]

I'm unfortunately expecting this getting worse with massive adoption of the drug but we can start with "Risk of Suicidal Thoughts and thoughts of self-harm with medicines known as GLP-1 receptor agonists,1 including Ozempic (semaglutide), Saxenda (liraglutide) and Wegovy (semaglutide)" - https://www.ema.europa.eu/en/news/ema-statement-ongoing-revi...

By the way - why are you so eager to promote this drug - can you please declare any conflict of interests?

[navjack27]

Wow...

  instead of ever more metabolic and mentally ill society living more like zombies than free human beings.

Literally just wow. What possesses you to say such a horrible thing?

[arijo]

Possess is a strong word - nevertheless you can start here if you want to be aware of what is going on in the real world:

Youtube Videos

https://youtu.be/PeqQd4_xveI?t=43

https://youtu.be/G0lTyhvOeJs?t=421

https://www.youtube.com/@metabolicmind

Books

https://a.co/d/cUAgokV

https://a.co/d/32zSKzo

https://a.co/d/acVla0y

[theshackleford]

Mental health treatment is not as widely available as it should be.