[mike_ivanov]

It's interesting that brain hypersynchronicity is a known source of epileptic seizures (among other things). This potentially could be a treatment for this specific problem.

See e.g.

  * https://www.sciencedirect.com/science/article/pii/S089662731930964X
  * https://onlinelibrary.wiley.com/doi/full/10.1111/j.1528-1167.2010.02805.x

[greentxt]

Doubtful. Shrooms cause seizures.

[asveikau]

Something tells me seizures have multiple causes and if the drugs is one cause it's not a cause for everybody.

[EasyMark]

I think so too. It’s like saying colds, covid, flu, nausea cause coughing, it’s a general symptom. Seizures are caused by many conditions.

[Doxin]

So do a lot of anti-epileptic drugs

[anothernewdude]

Guess what antidepressants cause?

[CacheRules]

Sources?

[__MatrixMan__]

Anecdotal, but I've tripped with two people who showed seizure like symptoms that they never had before or since.

Couldn't find any data at the time. Tried to get them to submit experience reports on erowid so that there would be some data out there, but they didn't want to put anything about it in writing.

[foobiekr]

Are you sure shrooms? If chocolates or gummies the compound therein is not quite the same as recent news stories have noted.

[__MatrixMan__]

Yeah, I grew them. I didn't sequence them for identification, but they were phenotypically P. Cubensis, as advertised on the spore syringe.

In neither case was it a big deal in the long run (not exactly great vibes in the short term though). I used to be a pretty enthusiastic user, so "just two times" is indeed uncommon.

Hopefully with the recent trend of decriminalization we can get together some respected data about this sort of thing. I still believe that psilocybin has been a net positive thing for most people who have tried it (including these two cases).

Even if the seizure thing were confirmed, all the conventional wisdom re: tripping remains unchanged. Be in a safe place with trusted people, consider a trip sitter, etc. On the other hand, I think having the data might help drive some better decisions: Situations you might avoid (e.g. swimming), etc.

[greentxt]

Can I get a cite on one of those news stories?

[muzani]

Yeah, I think data on this would be hard to get.

A tangential anecdote... I took a Pfizer COVID booster vaccine and saw my heart rate go up to resting above 100 on my calorie tracker watch. I talked with my doctor about this. He said he stayed away from the COVID boosters because they weren't a good balance of risk vs safety. I asked him whether high resting heart rates were a side effect. He said, no, there's no data for that, but there is data that it has an impact on heart rates.

I said, if there's no data, that means the vaccine isn't the source? He said, no, there's no data because I didn't report it.

[op00to]

Your heart rate increases in response to immune system activation. Like if you catch a cold or get a vaccine. Your doctor sounds like a quack.

[tambourine_man]

That doctor of yours should have their license revoked.

[muzani]

Thankfully in this country, we don't revoke licenses for telling people to submit health data.

[SoftTalker]

> I took a Pfizer COVID booster vaccine and saw my heart rate go up to resting above 100

Temporarily or permanently?

[zdragnar]

My brother has this permanently, though whether a delayed reaction to the booster or from when he got COVID itself (a relatively mild case) not long after, there's no way to know.

It has been a major detriment to his day to day life though. Any physically involved hobbies are impossible; just walking up a flight or two of stairs now leaves him completely winded for several minutes, as his heart rate also takes longer to come back to resting than before.

Would not recommend.

[muzani]

Temporary, but it wasn't clear at the time

[mistrial9]

ok - an underweight 20 year old woman who did not eat well before a Rolling Stones concert and then used cocaine and alcohol, also had a seizure.

goddam Mick Jagger !