Hacker News new | ask | show | jobs
by Lemontology 887 days ago
A multi-"salt" magnesium plus some glutathione antioxidant could temporarily calm some of the noise. Look into trans-cranial ultrasound (low power for 30-90 second sessions once or twice a day separated by at least 4 hours) (but this isn't even beyond trials yet), and Earthing which is stepping out barefoot onto the ground). Then vitamin C to recycle the glutathione, protecting it from its breakdown through its job.

All of these therapies would be calming inflammation and oxidative stress (both related to each other and to stray/excess electrical charges in the wrong places or out of control).

The magnesium I would use is "Magnesium Breakthrough" by "BIOptimizers" since it contains a large variety of salts. The bio-availability and especially the preferential uptake into specific organs...of Mg seems to be dependent on form, or salt.

And MIT students, a few years back, invented Magnesium-Threonate is also of therapeutic use as one possible tool, since it increases synapse density and neuroplasticity. Giving the chance of a brain to basically re-wire itself can be helpful when it is not functioning properly.

Lastly, fish oil, not snake oil, is going to help the body make the best membrane-encapsulated neuron bodies so that the brain is shuttling its neurotransmitters (which are basically signaling molecules) in a smooth and balanced functional pattern.

Other areas for YOU to RESEARCH before purchasing anything are these two things: Probiotics (like Seed DS-01), and Light. Look for a red and infrared light for winter and even summer use. It modifies the power of mitochondria. See this study: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3179978/#:~:tex....

It always helps to be the doctor but if you can't be for lack of time or dont have a naturally discerning mind, then get an opinion from a hormone or sports clinic which is designed to optimize, not a family doctor who wants food on kids' plates rather than competition with supplements. And your kid does need to eat food too, as a base. It might just be that doctors have an inborn instinct to protect their valuable secret knowledge from falling into three wrong hands like a Google algorithm unless you have the right keywords, then you'll be rewarded with the right knowledge. I'd like a conversation of such insights as you might have about this and autism, given the fact that also when I was a child, I felt like I was pretty much just watching the life around me and taking notes, or not developing attention and communicating with kids my age in school or making friends.

If you want your kid to talk more but they have autism, maybe introduce from an interest of their's to a conversational style designed to be technical and teach the vocabulary of the thing that they like learning about.

4 comments

> Look for a red and infrared light for winter and even summer use. It modifies the power of mitochondria. See this study: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3179978/#:~:tex....

getting regular zone 2 exercise is an extremely simple way to improve mitochondrial health. think a moderate-to-brisk walk up a hill.

The [empirical] study linked in my comment found that only 6-15% of Autistic people actually have a genetic disorder like fragile x.
Diagnosed, perhaps. Something like EDS is also a spectrum, you can have mild forms of it and not have them be enough of a concern to investigate, but obviously any amount of collagen disorder is going to have wide-ranging systemic effects.

There are a number of current studies looking more specifically into collagen disorders and autism and I expect them to find a broad correlation between the two.

Oral glutathione isn't bioavailable. You would have to inject it constantly to meaningfully raise your levels
It is with liposomal supplementation. This means that it has a surrounding lipid so microscopic balls containing the difficult to absorb substance (especially any thiol-containing molecular compounds) like Glutathione, can make it past without other peptides inhibiting its absorption.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6389332/

Thiols science: This research is informative for the topic of the role thiol compounds plays in the antioxidant system, of which, Glutathione is scientifically considered the body's master antioxidant, it recycling (think of "guarding") SOD (Super Oxide Dismutase) and Glutathione itself being recycled by Vitamin C. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7041647/

I'm forming a hypothesis tonight, as a "citizen scientist", that the very reason why thiols are hard to absorb is because thiols are often helping to get oxidized lipids and oxidizing chemicals OUT of the body in the two ways that can physically happen. It seems interesting to me.

NAC raises glutathione in serum and is extremely available.
Have you tried magnesium threonate? It's supposedly the only form that passes the blood brain barrier.
I have, and it was in a period of my life where I was taking all <sorts> of nootropics. Im sure you've heard of them but they're not just ADHD meds rebranded as mind enhancing or memory boosters like some of the hype would lead you to believe.

Ask me about my TEN K For The Mind. It is a stack I had fun designing in my free time and even if it never sees the light of day, it still will always be The Extraordinary Nootropic Kit For The Mind!

Tell me about the "ten k for the mind", please.
I think it might be off-topic here but maybe you can send me email. *see profile.