I don’t see why. Connection-wise, the node event would loop make I/o blocking from the http request / response side a non issue. I doubt the backend is doing physics heavy stuff for the front end.
There is still considerable overhead turning things into buffers and back. Was there ever a good reason given as to why passing an object to a worker normally has to convert everything to string and back? It is just so completely idiotic.
Node also only works off a single core.