[swyx]

i find it funny how the bryan johnsons of the world take like 123 pills every day and optimize all the fun out of life and we still dont really really know if it works or not

and then old geezers like munger and buffett do whatever the hell they want and outlive everybody

[ravenstine]

Jack LaLanne died at 96 years old, yet my grandpa who's eaten tons of Taco Bell for most of his life is alive at just a hair from that age. I wonder what people will think about the obsession with "longevity" in the likely outcome of David Sinclair or Andrew Huberman dying in their 80s or earlier.

[BiteCode_dev]

Peter attia adresses that in outlive: bias survivor.

People with good longevity genetic don't pay the price as much for their behavior, so they indulge in it and stand out.

But most people don't have that, and can only emulate a little their epigenetic by exercice, diet, etc.

[spacetimeuser5]

There a tribe in Ecuador with reduced height studied by Walter Longo etc. They have a mutation in their growth hormone receptor, that means that they experience less effect of human growth hormone, hence reduced height. And their lifestyle is rather unhealthy: alcohol, smoking, sugars, junk food, obesity etc. Yet they rarely experience diabetes, cancer etc probably due to reduced mTOR pathway activation.

In the context of this specific post regarding Charlie Munger, you can't say that it's genetics unless you measure specific genes. He could be 100x Bryan Johnson, but Bryan Johnson at least makes his protocols open for use. And Munger didn't even bother to make a genetics test with his curiosity, thus providing no essential value to human civilization.

[listenallyall]

Look up Jim Fixx... obsessed with running, introduced the sport to millions, constantly hyping up the health benefits... died at 52. Tragically sad.

[swyx]

i mean, even they would say n=1 is not science. but then if longevity science cant guarantee your living slightly longer then is it even worth it lol

[paulpauper]

genetics. they matter a ton . read the bios of really old people (100+ yrs old) and nothing really stands out beyond having a lot of family member who also lived a long time. I think a low-stress lifestyle helps a lot too.

[Difwif]

Not to downplay everything you said but you really think Charlie Munger led a low stress life?

[infecto]

Commenting only on their professional lives. Their investment strategy was generally not a high stress one, they clearly enjoy their work so one could assume their professional lives were generally low stress.

[cezart]

They lived frugal lives, with everything needed covered for probably 10'000 years ahead. Large families, plenty of friends and a lot of wisdom. Yeah, I think Charlie and Warren's life's have way less stress than most people do.

[throwaway2037]

This is a fair point. If you exclude the early part of his life, working as an asset manager is easy work. Most jobs are much more stressful. Basically, you sit around and read annual/quarterly reports and try to find the next company to buy. To be clear, this type of asset management is similar to private equity. They are buying whole companies. This business is much lower volatility than buying/selling stocks for fund management. Also: Fewer transactions. So I would say the 2nd half of his life was low stress (outsider's view, of course).

[antod]

Heh, I had Bryan Johnson and Brian Johnson mixed up for a while there.