[ravenstine]

Jack LaLanne died at 96 years old, yet my grandpa who's eaten tons of Taco Bell for most of his life is alive at just a hair from that age. I wonder what people will think about the obsession with "longevity" in the likely outcome of David Sinclair or Andrew Huberman dying in their 80s or earlier.

[BiteCode_dev]

Peter attia adresses that in outlive: bias survivor.

People with good longevity genetic don't pay the price as much for their behavior, so they indulge in it and stand out.

But most people don't have that, and can only emulate a little their epigenetic by exercice, diet, etc.

[spacetimeuser5]

There a tribe in Ecuador with reduced height studied by Walter Longo etc. They have a mutation in their growth hormone receptor, that means that they experience less effect of human growth hormone, hence reduced height. And their lifestyle is rather unhealthy: alcohol, smoking, sugars, junk food, obesity etc. Yet they rarely experience diabetes, cancer etc probably due to reduced mTOR pathway activation.

In the context of this specific post regarding Charlie Munger, you can't say that it's genetics unless you measure specific genes. He could be 100x Bryan Johnson, but Bryan Johnson at least makes his protocols open for use. And Munger didn't even bother to make a genetics test with his curiosity, thus providing no essential value to human civilization.

[listenallyall]

Look up Jim Fixx... obsessed with running, introduced the sport to millions, constantly hyping up the health benefits... died at 52. Tragically sad.

[swyx]

i mean, even they would say n=1 is not science. but then if longevity science cant guarantee your living slightly longer then is it even worth it lol