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by whats_a_quasar 1070 days ago
It doesn't sound that hard for a motivated amateur to synthesize. This is really really really not meant to be advice, but Erowid hosts two sets of instructions for LSD synthesis. The intro of one of them says: "It is rather difficult to make by total synthesis, but with the right starting materials (lysergic acid, ergotamine) it is as easy to produce as your average THC or amphetamine."

I get the impression most LSD is made and distributed by amateur chemists. Until it was torn down, the undergrad dorm Bexely at MIT was famous for synthesizing LSD (and possibly distributing beyond campus). So it seems like Stanley would have been able to learn to do it with a reasonable amount of effort.

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Most of the LSD had been made by a few big time chemists... Owsley, Nick Sand, William Pickard..

They are each responsible for probably tens of millions of doses.

On Pickard's arrest in late 90s (https://en.wikipedia.org/wiki/William_Leonard_Pickard) : According to court testimony, Pickard's lab produced up to a kilogram of LSD approximately every five weeks for short periods. Despite criticism for their methodology, the DEA contends that there was a 99.5% drop in the availability of LSD in the US in the two years following the arrest.[7] Pickard himself has long denied these claims. In his 2007 paper "International LSD Prevalence – Factors Affecting Proliferation and Control", Pickard suggests that since the 1960s, LSD production has always been de-centralized. As to a turn-of-the-century decline in availability due to his own arrest, Pickard highlights the fact that LSD availability had been on the decline since 1996, a fact which he correlates in part with the exponential growth of availability and demand for MDMA and other hallucinogenic drugs.[8] The actual quantity of LSD seized by the DEA remains unclear, with figures ranging from 198.9 grams to 41.3 kilograms (410 million 100 µg hits of LSD).[9]

Nick Sand estimated that he produced about 140 million doses in his lifetime. (https://www.latimes.com/local/lanow/la-me-nicholas-sand-2017...)