[colecut]

Most of the LSD had been made by a few big time chemists... Owsley, Nick Sand, William Pickard..

They are each responsible for probably tens of millions of doses.

On Pickard's arrest in late 90s (https://en.wikipedia.org/wiki/William_Leonard_Pickard) : According to court testimony, Pickard's lab produced up to a kilogram of LSD approximately every five weeks for short periods. Despite criticism for their methodology, the DEA contends that there was a 99.5% drop in the availability of LSD in the US in the two years following the arrest.[7] Pickard himself has long denied these claims. In his 2007 paper "International LSD Prevalence – Factors Affecting Proliferation and Control", Pickard suggests that since the 1960s, LSD production has always been de-centralized. As to a turn-of-the-century decline in availability due to his own arrest, Pickard highlights the fact that LSD availability had been on the decline since 1996, a fact which he correlates in part with the exponential growth of availability and demand for MDMA and other hallucinogenic drugs.[8] The actual quantity of LSD seized by the DEA remains unclear, with figures ranging from 198.9 grams to 41.3 kilograms (410 million 100 µg hits of LSD).[9]

Nick Sand estimated that he produced about 140 million doses in his lifetime. (https://www.latimes.com/local/lanow/la-me-nicholas-sand-2017...)