[runnerup]

TUDCA is not perfectly safe. Studies show that while it does prevent damage from ethanol and AAS abuse when taken during or after, it can also cause/exacerbate damage when taken prior to ethanol/AAS or by healthy individuals.

Long term TUDCA use seems like it also lowers good cholesterol.

[graeme]

To be clear, if you’re not taking alcohol/ethanol etc then TUDCA seems fairly safe for short term use

[runnerup]

For <8 weeks, yes. But year-round general supplementation for no indicated reason can be harmful. TUDCA is known to lower HDL cholesterol (good cholesterol).[0]

NAC would be a more appropriate year-round liver support for general supplementation.

0: https://pubmed.ncbi.nlm.nih.gov/8674405/

[manmal]

NAC chelates metals like zinc and copper, so you got to watch out for low levels of those when supplementing NAC.

[graeme]

Even that has issues. It can promote lung cancer growth and initiation. The gist is it is too good at keeping cells alive and keeps alive some that should have died.

https://www.science.org/content/blog-post/n-acetyl-cysteine-...

[erentz]

Oh that’s not good. Thanks for letting me know.

[TedDoesntTalk]

What is AAS?

[runnerup]

Anabolic steroids, it’s popular in that community as a harm reduction supplement for liver support.