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by graeme 1215 days ago
To be clear, if you’re not taking alcohol/ethanol etc then TUDCA seems fairly safe for short term use
1 comments

For <8 weeks, yes. But year-round general supplementation for no indicated reason can be harmful. TUDCA is known to lower HDL cholesterol (good cholesterol).[0]

NAC would be a more appropriate year-round liver support for general supplementation.

0: https://pubmed.ncbi.nlm.nih.gov/8674405/

NAC chelates metals like zinc and copper, so you got to watch out for low levels of those when supplementing NAC.
Even that has issues. It can promote lung cancer growth and initiation. The gist is it is too good at keeping cells alive and keeps alive some that should have died.

https://www.science.org/content/blog-post/n-acetyl-cysteine-...