The mRNA-based covid shots (and the adenovirus-vector covid shots) are a wee bit different in how they operate than pre-covid vaccines.
Modified covid spike proteins are produced by host (i.e. a vaccinee's) cells. The spike proteins are anchored within the cells but "poke out" through the cellular membranes so they're able to elicit an immune system response.
The cells expressing the mod-spike are ultimately destroyed. If you review pop-sci / marketing materials produced by Pfizer and Moderna and government agencies and non-profits who promoted the shots, the fate of these cells will be glossed over, but that's what happens.
This is why it was important that the contents of the jabs stayed in the muscle tissue near the injection site and the process of translating all of the vax mRNA into mod-spike be rapid. If vax mRNA travelled around via the circulatory system and was taken up by cells in, say, the walls of blood vessels throughout the body or cells in the heart or pericardium or in other tissues, then some cells in those locales would be destroyed and, if enough cells in the wrong place at the wrong time were destroyed this way, bad things could happen. Observing vax mRNA persisting or existing weeks and weeks post-administration is not good for this (and additional) reasons.
Everything he's saying is common knowledge to anyone who has researched this topic. Having a background in bioscience would not help and most likely hurt, because people within those fields are highly incentivized to suppress bad news about their prior actions.
> If vax mRNA travelled around via the circulatory system and was taken up by cells in, say, the walls of blood vessels throughout the body or cells in the heart or pericardium or in other tissues, then some cells in those locales would be destroyed…
This is something that you would consider to be common knowledge?
To anyone who has researched this topic, yes, and many other things. How do you think the mRNA vaccines work? If you got interested in vaccines around the middle of 2021 and started finding and subscribing to the right blogs and people, you know a whole lot of things about this topic that other people don't. These sorts of threads are a bit frustrating because it involves watching people catch up to where we were 12 months ago.
Can you link me to the papers that make that particular paragraph obvious?
Also can you elaborate on why having prior knowledge on this topic disqualifies you from being knowledgeable on this topic?
Wouldn’t the papers you’ve read have been written by people in the field of immunology or bioscience? How are those people not disqualified due to prior knowledge?
edit: Also please elaborate on how I identify the “right” blogs.
Sorry this is frustrating for you. I do not regularly come to HN for biology knowledge from software devs that can’t seem to provide any sources or credentials. What GP is trying to convey comes pretty close to medical advice and “people that have studied this professionally are categorically untrustworthy” seems a bit like some uh, less than germane bullshit, to be frank.
Is that true? I remember my daughter had a severe bacterial infection and they couldn't get an IV in her so they did an intramuscular injection of antibiotics.
Modified covid spike proteins are produced by host (i.e. a vaccinee's) cells. The spike proteins are anchored within the cells but "poke out" through the cellular membranes so they're able to elicit an immune system response.
The cells expressing the mod-spike are ultimately destroyed. If you review pop-sci / marketing materials produced by Pfizer and Moderna and government agencies and non-profits who promoted the shots, the fate of these cells will be glossed over, but that's what happens.
This is why it was important that the contents of the jabs stayed in the muscle tissue near the injection site and the process of translating all of the vax mRNA into mod-spike be rapid. If vax mRNA travelled around via the circulatory system and was taken up by cells in, say, the walls of blood vessels throughout the body or cells in the heart or pericardium or in other tissues, then some cells in those locales would be destroyed and, if enough cells in the wrong place at the wrong time were destroyed this way, bad things could happen. Observing vax mRNA persisting or existing weeks and weeks post-administration is not good for this (and additional) reasons.