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by disabled 1358 days ago
This is fairly well known.

But generally, these tips are the way to go: https://www.ted.com/talks/sandrine_thuret_you_can_grow_new_b...

Anyways, I personally take:

1. nano encapsulated punicic acid (called Granagard), which crosses the blood brain barrier effectively (search "nano-pso" on Google Scholar)

2. sulforaphane/sulphoraphane (spelling depends on where you are located)

3. co-ultramicronized palmitoylethanolamide + luteolin

4. ubiquinol

5. methylated b vitamins (~50% of the population has a MTHFR variant that generally requires you to need methylated B vitamins, versus regular B vitamins)

6. high doses of gamma linolenic acid (I use evening primrose oil and Jarrow brand is trusted)

7. algae omega 3

3 comments

>sulforaphane/sulphoraphane

How do you take this? I've tried broccoli supplements and they don't work all that well. There's only one direct sulforaphane supplement that I've found, though I'm not sure whether to trust the brand

I take capsules, 2x/day. I take sulphoraphane 140 mg/day.

Jarrow and Thorne Research are reliable brands. But, Thorne Research tends to be way overpriced in my opinion. As you know, you never ever buy supplements off of Amazon or places that are not well heard of.

Jarrow: https://www.iherb.com/pr/jarrow-formulas-broccomax-120-delay...

Thorne Research: https://www.iherb.com/pr/thorne-research-crucera-sgs-60-caps...

Do you notice a difference?
One of those disturbing things about nootropics is that people frequently stack a large number of them so the effects of any particular one is unclear.

There are also questions about what exactly a substance is.

Years ago I bought a tub of Piracetam that felt a little bit like that stuff in the movie Limitless. No Piracetam I bought afterwards felt that way so I wonder if I'd really gotten something more like amphetamine.

> Years ago I bought a tub of Piracetam that felt a little bit like that stuff in the movie Limitless. No Piracetam I bought afterwards felt that way so I wonder if I'd really gotten something more like amphetamine.

Years ago, I bought some Piracetam when I was traveling in Asia. One of my relatives, who's an MD, didn't want me to take it and did some research in actual medical databases. IIRC, he said pretty all the articles praising it traced back to a single study.

It's really understudied in US medicine. In Russia, it's been used for a long time as a general purpose brain enhancer. FWIW
In general though, hasn't it been understudied?
I experimented with nootropics in the past and currently I just stick to vitamin D3 + K2 + Omega 3 (DHA/EPA). In case I need to focus I just add 300/600mg of Alpha GPC (but I don't use it frequently, once I start to become irritable it means there's enough acetylcholine in my brain).
My biggest worry is always the placebo effect.
There is nothing to worry about?
Why worry, if it works?
This has nothing to do with nootropics.

I have more than a few neurological issues. I have 3 medication induced movement disorders. I also have 2 rare immune mediated neurological diseases affecting my peripheral nervous system.

Anyways, the stuff I take is to ensure adequate nutrients for my brain. But the primary goal is for neuroregeneration over the long term.

Do you mind sharing where one sources such an esoteric pharmacopia?!
I get Granagard from https://granalix.com.

I get the co-ultramicronized palmitoylethalinomide + Luteolin from http://epitech.it, but you have to use a package forwarding service to mail to US (they don’t ship to US, even though it is Italy based and 100% legal)

The rest I get from https://iHerb.com

As I said, I am not interested at all in nootropics or peptides. It is basically all antioxidants/natural neuroregenerative compound/omega fatty acids.

Reddit r/peptides and r/nootropics like a lot of these substances. Also u/Misteryouaresodumb of NootropicsDepot is a wealth of knowledge. There’s a long tail of YouTube and other sources you’ll find from there.
Fish cooked in ghee. Both are rich in omega3. And you will notice a difference haha.
thank you for this list! imma try all this! to see for myself
That's a great idea! Try a random list of things that some stranger on the Internet has recommended