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by akkawwakka 1440 days ago
We are preventing development of serious disease with the vaccine. At the end of the day, that’s what should count.
1 comments

> At the end of the day, that’s what should count.

no, that's just the most that could be achieved. The ideal, which is long lasting immunity, is not quite achievable atm (it seems).

I'd definitely accept reduction in severity, but would hope for a life long immunity.

The conversation around this could benefit from more precise language.

Long lived immunity against severe disease, driven by the T cell response against epitopes that are generally well preserved (>80% for spike protein, ~98% for non spike protein) [1]

Immunity against infection, conferred by circulating neutralizing antibody, which last for a couple of months

Most vaccines blunt or prevent disease but not infection.

[1]: https://www.nature.com/articles/s41423-022-00838-5