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by chii
1440 days ago
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> At the end of the day, that’s what should count. no, that's just the most that could be achieved. The ideal, which is long lasting immunity, is not quite achievable atm (it seems). I'd definitely accept reduction in severity, but would hope for a life long immunity. |
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Long lived immunity against severe disease, driven by the T cell response against epitopes that are generally well preserved (>80% for spike protein, ~98% for non spike protein) [1]
≠
Immunity against infection, conferred by circulating neutralizing antibody, which last for a couple of months
Most vaccines blunt or prevent disease but not infection.
[1]: https://www.nature.com/articles/s41423-022-00838-5