[technick]

I run a small digitalocean instance with just postfix running on it that forwards to my real email address at gmail, using aliases. It takes me under 15 seconds to log in, create a new aliases, and run 'newaliases'. This way I can keep aliases around that are important and when they start spamming, just go delete it until I need it again.

[hardwaresofton]

If you're considering running postfix, IMO you should consider running maddy/chasquid instead:

https://github.com/foxcpp/maddy

https://blitiri.com.ar/p/chasquid/

They're simpler, and maddy (at least) has an S3 backend now.

[selcuka]

Isn't it easier to just catch-all and blacklist the spamming ones?