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by tomatowurst 1508 days ago
5000 IU is really too much. At best 2000, 2500 IU is good.
5 comments

No, 5000 IU per day is generally considered the highest non megadose. Make sure it is good quality (D3, USP in the US), and it should be fine. Some people say also to take K2 (also make sure it's USP in the US), but I'm not sure the exact supposed mechanism of protection from adverse effects from D3. Something about preventing calcium from leaching from the bones and accumulating in the blood, I think.
"Vitamin D controls the absorption of calcium into the blood. Vitamin K2 controls where that calcium ends up.

"Over-supplementation of vitamin D3 without ample vitamin K2 leads to problems of excess calcium.

"If calcium isn’t laid into bone, it will find itself in other tissues, like your arteries. Calcium in the arteries is BAD. It contributes to atherosclerosis and vessel stiffness."

https://dralexrinehart.com/articles/the-vitamin-d-and-vitami...

Unless you are a doctor that has been monitoring the poster, you have no idea if that is true. My blood levels are consistently deficient when I’m not taking 10,000 IU/day (and this is with a fair amount of daily sun exposure.) People have widely varying needs.
I use 60,000 to 90,000 IU's per day and have been doing so for years. The most I have taken in a 24 hour period is 140,000 IU's. There is no way I could have started off at those levels however. It would have induced major hypercalcemia had I done that prior to mobilizing all the stored/misplaced calcium in my gut and vasculature. I am not suggesting anyone else do this. One must have a specific need when doing this.

I only mention this to say that one can go well above the RDA/RDI that are highly contested to be far too low for modern diets, environmental inputs and lifestyles.

> Taking 60,000 international units (IU) a day of vitamin D for several months has been shown to cause toxicity. This level is many times higher than the U.S. Recommended Dietary Allowance (RDA) for most adults of 600 IU of vitamin D a day. [0]

I think you may be poisoning yourself.

[0] https://www.mayoclinic.org/healthy-lifestyle/nutrition-and-h...

That would certainly be true had I done that from day one as I had mentioned. Their documentation as with most medical documentation is based on the lowest common denominators. They will not risk explaining why one might do what I am doing.
It seems true without qualification.

What you're saying here has a lot in common with "woo", I hope you realize.

I suppose time will tell. I've been doing this a number of years. I will check back in a few more years to see how things are going. Honestly the cholecalciferol levels are the least taboo of the biohacking I do with myself. The more risky testing I did was to see how high I could go on the tocotrienols, tocopherols and fibrinolytic enzymes before I ran into bleeding.
Aren't you concerned that your data is super subjective as you're collecting it on yourself?

It sounds like there are a ton of confounding variables possible, not to mention your own personal biases in interpreting any potential causality.

the 600 IU RDA is clearly a mistake in an earlier publication. it should be 10x that.
No, 600 IU (15mcg) is the actual RDA. There's a lot of belief that it's an error, but it's not a typographical error.
The actual RDA is not correct.
It is more correct than the research that shows otherwise.
The dose they claim to be taking is 100x that, not 10x.
That's a crazy amount. I had a very low blood test started supplementing with k2/5000 vitamin d several years ago and my blood levels have been fine ever since.
How much K2 are you taking?
100mcg for each initial 5000 IU's for the day but I stop at 800mcg of K2 MK-7 regardless. I sometimes also take K2 MK-4 in addition to that. I also get a small amount of K2 from eggs.
5000 isn't too much when you're catching up from a deficiency.
I took 15k IU daily (at the advice of my doctor) for several months at one point to get my levels back up. I don't remember the numbers, but my levels were extremely low.
It really depends on the person. You just need to monitor your blood levels