[georgyo]

The main guix monorepo may set that hard requirement the everything just be built from source, but if you want to run closed source software than your only two options are make a fake FHS or use patchelf. Both methods have pros and cons. Only patchelf makes the result work well with other closed source programs.

While from a philosophical point of view guix is pure, real world usage often needs closed source software.

[rekado]

Yes, for pre-built binaries you can't really get around patchelf. For example, that's also how CUDA is packaged for Guix.