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by ceejayoz 1668 days ago
> The specific targeting makes it easier to allude the vaccine as only a small part of it has to mutate.

Nothing says an mRNA vaccine can't express more than one protein.

That said, I'm talking more about being able to target a portion of the virus that's more fragile than others - somewhere a mutation is likely to make the virus useless if a mutation occurs there.

(The ability to rapidly adjust for mutations is a bonus, too. I'm hoping we get to a regulatory regime eventually where they can tweak overnight and produce fairly locally.)

> There was a study that natural immunity was more effective against the virus and variants because of this.

There's information in the other direction now. https://news.yahoo.com/vaccine-confers-better-protection-tha...

2 comments

> There's information in the other direction now. https://news.yahoo.com/vaccine-confers-better-protection-tha...

The way they conducted that study was terrible, read the qualifications and the limitations in the discussion at the bottom.

Personally the Israeli study looks a lot more sound.

Sigh, what isn't biased these days? No need to poison the well, the article is clear and sound (to me at least) regardless of who wrote it and why. Do you have any arguments against it? Or your own better analysis of the two studies?
It really annoys me how people disregard what "the other side" is saying just because it's them saying it. Just adds to the polarization. And it annoys me because I used to do the same.
> Please don't post shallow dismissals, especially of other people's work. A good critical comment teaches us something.

You may want to refute the points instead of attacking the source.

What did you take issue with in their analysis?

Maybe this is a less biased source? Dr John Campbell: https://www.youtube.com/watch?v=9bamaEMftg4
> I'm hoping we get to a regulatory regime eventually where they can tweak overnight and produce fairly locally.

I don't think that's likely. Even if a scientist was able to adjust a vaccine overnight, you'd still need to do a clinical trial to verify that the vaccine doesn't accidentally target something that it shouldn't.