Mainly sugar causes a secretion of insulin, as you seem to know. But you seem to assume that insulin or frequent high insulin levels cause insulin resistance. As far as I know, that's not the case. Insulin sensitivity can be affected by many different factors and it's not perfectly understood why cells become insulin resistant. Known risk factors that can lead to insulin resistance include obesity, genetic factors and inflammation.
> But you seem to assume that insulin or frequent high insulin levels cause insulin resistance.
In another comment You stated obesity causes T2D. As I previously stated there are obese people that do not get T2D, but more importantly there are skinny people who get T2D.
In response you replied to another comment claiming there are medical cases where people who do not eat carbs get T2D in attempt to disprove my position. Again I ask you to link a single case of T2D where the patient did not consume carbs/sugars. It would be the same as trying to find a case of non alcoholic fatty liver disease where the patient does not consume carbs/sugars, another chronic condition that is linked to obesity but not cause by obesity, it is cause by chronic damage to the liver by way of processing sugar, like T2D it just doesn’t happen without carbs/sugars.
Consider that in many - not all - cases of pre-diabetes and even full T2D, patients can make dietary/lifestyle changes to reverse their insulin resistance and even get off medication entirely. Reversing T2D is successfully done by reduction of sugar/carb consumption, it can be but doesn’t need to be a ketogenic diet. But I have never heard of any case where a patient successfully reversed T2D with weight loss alone without reduction of carb/sugar intake.
This is a common misconception. Insulin resistance and type 2 diabetes is mostly caused by obesity.
Sugar has a relatively high caloric density and can be addictive, leading to obesity. However, you can eat large amounts of sugar if you do a lot of sport, for example, and then burn off the calories again. Then you don't get diabetes from it either.
> mdbug: Insulin resistance and type 2 diabetes is mostly caused by obesity.
Your statements are misleading. Sugar can be addictive. Sugar can also cause obesity. Sugar can also cause insulin resistance. Sugar can also cause diabetes. These concepts are not mutually exclusive.
The reviewed evidence supports the theory that, in some circumstances, intermittent access to sugar can lead to behavior and neurochemical changes that resemble the effects of a substance of abuse.
It is thought that SSBs contribute to weight gain in part by incomplete compensation for energy at subsequent meals following intake of liquid calories. They may also increase risk of T2DM and CVD as a contributor to a high dietary glycemic load leading to inflammation, insulin resistance and impaired beta-cell function.
Temporal patterns over the past three to four decades have shown a close parallel between the rise in added sugar intake and the global obesity and type 2 diabetes (T2D) epidemics.
The incidence of T2D increased dramatically over the last decades mainly due to Western lifestyle factors such as lack of exercise and high calorie diets. In fact, high-sugar diets are thought to promote weight gain and insulin resistance predisposing to T2D
There are plausible mechanisms and research evidence that supports the suggestion that consumption of excess sugar promotes the development of cardiovascular disease (CVD) and type 2 diabetes (T2DM) both directly and indirectly.
> Sugar has a relatively high caloric density and can be addictive, leading to obesity.
Blood sugar triggers the release of insulin to clear it from the blood. Insulin is a hormone that puts the body into an anabolic state so all cells and in particular fat cells begin to store the sugar from the blood. There is a correlation between obesity and T2D, but not causation.
This is why not all T2D patients are obese, rather in every case of T2D you will find someone that regularly consumed sugar/carbs.
Can you link to any medical case where the patient did not consume any carbs/sugars and still became insulin resistant?
If a patient consumes no carbs, there would be no high levels of blood sugar, no need for insulin to clear excess sugar from the blood…so I’d really like to see what the medical treatment would be for such a patient.
T2D is insulin resistance, what causes the body to release insulin and why does the body become resistant?