[TheManInThePub]

> Johnson and Johnson - which just payed out on a case relating to cancer from baby-powders

I asked this question in another post and did not get a reply.

The US links sited state no evidence for talc causing cancer. A search of the NHS website also suggests no clear evidence [1]. Cancer Research (a respected UK charity) give a layman's summary (albeit focusing on ovarian cancer), stating no clear evidence and pointing out that there are far more serious risks to worry about [2].

Given the above, what is the hype about? Is this because the US is so insanely litigious?

[1] https://www.evidence.nhs.uk/search?om=[{%22ety%22:[%22Inform...

[2] https://www.cancerresearchuk.org/about-cancer/causes-of-canc...

EDIT: Down votes for asking a genuine question? Shame on you.

[mikeyouse]

We know that asbestos causes mesothelioma and that J&J baby powders contained asbestos since talc/asbestos are often found together in mines.

J&J knew for decades that they were shipping asbestos to consumers in a powder form that's regularly inhaled -- they ghost-wrote and sponsored studies to deny that asbestos existed in their products and lied to the FDA in their disclosures..

https://www.reuters.com/investigates/special-report/johnsona...

It seems that most talc doesn't cause cancer -- but some talc has "rather high" amounts of asbestos in it -- which we know causes cancer.

[saul_goodman]

And guess what? Aftermarket brake pads are still made with asbestos! New vehicles sold in North America no longer have asbestos pads, but if you have had a vehicle long enough to have new pads put on then your car almost certainly has asbestos pads now!

https://www.theasbestosinstitute.com/2020/05/27/asbestos-in-... https://www.autoserviceworld.com/jobbernews/growing-threat-a...

So, if you happen to still do your own brake work, remember to spray down the parts with a water mister before you handle them to keep the dust from getting into the air. Vacuuming up any brake dust left behind is probably a bad idea too, wetting it down and handling as a liquid is safer.

[cyounkins]

As far as I know most OEM and aftermarket brake pads still contain asbestos and there is no ban on them. I read your links but they don't support the statement, "New vehicles sold in North America no longer have asbestos pads".

[dghughes]

And talc is used in many products not just Johnson & Johnson baby powder. Many are things paint, plastics, paper, rubber, insulation, ceramics. But talc in cosmetics is probably the one way where people would be applying it to their skin for long periods of time.

[TheManInThePub]

> It seems that most talc doesn't cause cancer -- but some talc has "rather high" amounts of asbestos in it -- which we know causes cancer.

So no evidence, just suspicion?

I must be blunt and say this has left me more puzzled why the US courts have ruled the way they have.

EDIT: Down votes again for asking a question? Explain yourselves. Are people defending something without evidence?

[njovin]

From the parent comment's link:

> A Reuters examination of many of those documents, as well as deposition and trial testimony, shows that from at least 1971 to the early 2000s, the company’s raw talc and finished powders sometimes tested positive for small amounts of asbestos, and that company executives, mine managers, scientists, doctors and lawyers fretted over the problem and how to address it while failing to disclose it to regulators or the public.

I think you're being downvoted for not RTFA, not for asking a question.

[TheManInThePub]

> sometimes tested positive for small amounts of asbestos

And the question I have asked is where is the evidence that such small quantities are a risk? The UK links I have posted suggest otherwise. This is why I am asking.

I'm puzzled... are the US courts are saying "OMG Asbestos" rather than looking at safe levels? What if the same courts said "OMG 5G" ! This is why I am asking a genuine question.

[rkk3]

Because there is no safe level of exposure to asbestos.

From the above Reuters article "The World Health Organization and other authorities recognize no safe level of exposure to asbestos. While most people exposed never develop cancer, for some, even small amounts of asbestos are enough to trigger the disease years later."

https://www.reuters.com/investigates/special-report/johnsona...

[acomjean]

Asbestos has to be in a “friable” form for it to be bad. The particles are so small they can get into deep your lungs.

I actually was at a landfill expansion project where a backhoe digging down through the trash hit some bags labeled asbestos. I’m glad it was raining. Also worked in a building with asbestos in the floor tiles. Fine when not disturbed, but anytime they had to remove them it was a production.

https://ehs.oregonstate.edu/asb-when

https://www.fs.fed.us/eng/toolbox/haz/haz07b.htm

[throwawaysea]

Interestingly some uses of asbestos aren’t actually banned, which is very surprising to me: https://www.snopes.com/fact-check/is-epa-allowing-asbestos-p...

[makomk]

As I understand it, there's also trace levels of naturally-occurring asbestos pretty much everywhere humans live, so there's also no way to completely avoid exposure.

[TheManInThePub]

> Because there is no safe level of exposure to asbestos.

I think we are getting to the bottom of this :-)

The UK Health and Safety Executive state...

"The control limit for asbestos is 0.1 asbestos fibres per cubic centimetre of air (0.1 f/cm3). The control limit is not a 'safe' level and exposure from work activities involving asbestos must be reduced to as far below the control limit as possible."[1]

Maybe this is where the differences arise. The UK are comfortable with a minimum practical level where risks are very low, whereas the US state none at all.

Thank you for helping answer a question and not mindlessly clicking on down vote. HN is beginning to turn into Reddit rather than seeking inquisitive technical/scientific conversation.

[1] https://www.hse.gov.uk/asbestos/regulations.htm

[headmelted]

That’s not the question you asked and you know it.

That said, it is very much known that there are no safe levels of exposure. We know this from case data, but also pretty horrifically from workers who inadvertently gave their family members terminal illnesses later in life because they carried what would have at the time been considered fairly trivial amounts of loose dust home on their shoes/overalls/hair.

[alsetmusic]

If this gets another “shame on you” edit, I’d reflect on we people are downvoting you. Fwiw, I haven’t voted on your comments either way.

[TheManInThePub]

If people could explain why they are down voting honest questions I would appreciate it.

I've never heard of claimed talc-cancer links in the UK.

[0xFF0123]

As other comments have pointed out, talcum powder in its pure form is talc, which is a mineral and safe. The issue is that some cosmetics were contaminated with asbestos, which is not safe.

[gmadsen]

conspiracy to falsify info to regulators is a crime by itself

[contrahax]

The information in the article posted by the person you're responding to answers your questions - J&J knew their product had high levels of asbestos and hid it from regulators while doing nothing about it. There absolutely was evidence of this, if you would read any of the information posted above. If I sold you a bottle of water with enough asbestos in it to give you cancer, knew about it, and didn't tell you: that would be illegal - it is pretty straightforward.

[foerbert]

Can't even downvote myself, but my guess is that it's related to the extremity of your position. It sounds a lot like you're saying since we know cyanide is poisonous by itself, it's very strange to be able to win a lawsuit if you find significant amounts of cyanide in your bread. Most bread is fine, right? So merely finding cyanide in it should only count as suspicion of a problem and not count as evidence... seems to be what you're saying.

[TheManInThePub]

Cyanide occurs naturally in apple cores. It is the dose that makes the poison.

The UK links I have cited say the low levels are not an issue. I've genuinely asked what evidence the US courts are using and I appear to have come up against group think. I did not expect this on HN.

I'd genuinely appreciate it if somebody can provide evidence citing the risk is other than negligible.

[foerbert]

This is why I specified significant amounts, but the exact details of my highly contrived example are obviously not that important.

If you phrased it the way you phased this response, I think you would have gotten a better response.

You didn't phrase it as "I have reason to believe certain levels are not a problem, and I am unaware of the levels recorded in the lawsuit. Where they high enough to be a problem?"

You instead phrased it far more absolute terms that stated that 'merely' finding a dangerous substance in a product was not evidence of it being dangerous. It absolutely is evidence. It may not be sufficient evidence on it's own, but each piece of evidence does not need to be sufficient to prove the case entirely on it's own. Your statements have also carried the extremely strong implication - and that's being generous - that the US courts were definitely wrong. I don't think anybody read your posts and thought you were requesting information and not stating a strong position in defense of J&J.

People have limited time and effort. You made it as difficult as possible to get the information you wished. I wouldn't blame this one on HN groupthink.

[craftinator]

Asbestos -> Cancer.

Safe amount = 0.

[Google234]

Radiation also -> cancer. Should we ban windows that allow sun light into our lives??

[TheManInThePub]

What an inane response. Perhaps I can counter with

Alcohol -> Cancer.

Safe amount = 0.

Alcohol content of fresh bread > 0

[telchar]

That's an interesting example to choose, because almonds have a small amount of cyanide naturally. I think that highlights that quantity matters

[jacobwilliamroy]

The evidence is that there was enough asbestos in the talc to cause cancer, and multiple executives at Johnson and Johnson knew, and people who used it got cancer. I'm not sure how you could believe the people who unknowingly inhaled asbestos and rubbed it all over their babies do not have standing.

[TheManInThePub]

Thank you for being the first person to post an informative reply rather than down voting a question. HN is turning into reddit.

> I'm not sure how you could believe

Though this is unnecessarily insulting.

> the people who unknowingly inhaled asbestos and rubbed it all over their babies do not have standing.

If the concentration was so low as to be negligible (as the links I have posted state) then why the successful litigation? This is the question I am asking!

> The evidence is that there was enough asbestos in the talc to cause cancer,

This is the evidence I am asking for. The NHS and other respected UK bodies state differently. This seams to be a purely US issue and I am asking why.

[jacobwilliamroy]

Researchers at Johnson & Johnson detected unsafe levels of asbestos in the talc as part of their own internal testing. There are internal emails that show high level executives asking researchers to switch to a less sensitive test which would allow them to make the concentration of asbestos appear lower than it really was. I remember that when the story first dropped, the people writing J&J's press releases were very careful to use only the present tense when discussing the asbestos levels in their talcum products which implies to me that they did eventually rectify it. That's all I know. I didn't follow the story for very long.

[ad404b8a372f2b9]

It's not uncommon, science does not hold the ultimate truth of the world, it's a complex system based on intuition and beliefs and politics. Medical responsibility is highly complex and it does not follow the same rules (thankfully). In Europe, courts have been compensating people who got multiple sclerosis induced by the Hep B vaccine for decades even though there is no evidence of a causal link.

[ceejayoz]

> Is this because the US is so insanely litigious?

Part of it is the weird setup of jury trials for civil cases, especially impactful in cases revolving around fairly technical, detail-oriented stuff like malpractice.

Twelve randomly selected lay people may not be the best determiners of scientific evidence and in-depth statistical analysis.

[linuxftw]

It's enough to put people to death, so it should be enough for everything else.

[ceejayoz]

Twelve randomly selected lay people shouldn't get to decide to allow the State to kill people, either.

[linuxftw]

No argument here. I was just point out how trivial our systems are, and we still kill other humans based on the feelings other humans.

[seiferteric]

At least that requires unanimous decisions vs civil cases where it just has to be the majority.

[ceejayoz]

The legal standard for a conviction/judgement also changes, from "beyond a reasonable doubt" in criminal to "preponderance of the evidence" in civil- i.e. 99.9% certainty becomes 51% certainty.

[nitwit005]

Every criminal case involves more than a jury. The prosecutor has to decide to bring charges, judge has to accept the case, etc. Death penalty cases are more involved. I've sat through the automatic appeals that were part of California's process.

[matco11]

Talc is a mineral in clay mined from underground deposits. It’s the softest mineral known to man and that makes it useful in a wide range of consumer and industrial products. Asbestos is also found underground, and veins of it can often be found in talc deposits, leading to a risk of cross-contamination, geologists say.

Full article here: https://www.nytimes.com/2018/12/14/business/talc-asbestos-po...

[kvna]

It’s presumably not the talc but the asbestos found in the talc deposits that makes its way into the baby powder

[pkaye]

Talc comes from the ground so sometimes there are veins of asbestos deposits interspersed. I think they screen out those sections with high asbestos contents but it might not be perfect enough so there might be trace contents.

[ineedasername]

It wasn't the talc, it was the asbestos located near the mines and showed up in samples taken over the years, which J&J also obscured and best and covered up at worst.

[swiley]

>The US links sited state no evidence for causing cancer.

It's benzine. It's a known carcinogen, no need for empiricism here.

[ceejayoz]

There are lots of known carcinogens for which the dosage is important. For example... sunlight.

There's a reason the "this product contains a chemical known to the State of California to cause cancer" warning labels are a bit of a joke, after all.

[nyolfen]

benzene is not one of those

[ceejayoz]

One molecule of benzene will guarantee a cancer case?

[rkk3]

You aren't guaranteed to die from being shot in the head either. However there are things which the medical community recognizes have no safe level of exposure.

From the original article: "The toxicity of benzene in humans has been well established for over 120 years. The hematotoxicity of benzene has been described as early as 1897. A study from 1939 on benzene stated that “exposure over a long period of time to any concentration of benzene greater than zero is not safe,” which is a comment reiterated in a 2010 review of benzene research specifically stating “There is probably no safe level of exposure to benzene, and all exposures constitute some risk in a linear, if not supralinear, and additive fashion.”

[mr_toad]

Yeah and you literally can’t breathe without risking being exposed to benzene. It’s in many adhesives, paints and petrol.

If you want to adopt a zero tolerance policy for benzene then you’d need to ban petrol. Or stop breathing.

[Google234]

It just takes one UV ray hit one strand of dna and lead to cancer.

[adrianmonk]

The links are about talcum powder, not sunscreen. Totally separate type of product that has nothing to do with benzene.

[gameswithgo]

I see people started downvoting this, if you do, please explain why.

[dqv]

You have got to give people more than 6 minutes to respond with a counter-argument, especially if you want a thoughtful answer.

[jacksnipe]

Because J&J didn't get in trouble for talc being carcinogenic. J&J got in trouble for their talc being contaminated with asbestos, which is definitely carcinogenic.