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by ellimilial 1853 days ago
Quite possible. Nobody wants another hERG fiasco.
2 comments

Did someone try editing out hERG?!
A fair amount of drugs inhibiting it had to be recalled after https://pubmed.ncbi.nlm.nih.gov/16554806 and subsequent regulators actions.
Oh, OK -- right hERG inhibition liability is a candidate killer. It's just since the topic was gene editing, I thought someone had experimented with editing hERG somehow which had me really confused.
ether-a-go-go-related ... LOL
TIL gogo dancers are probably named after a legendary rock club named „Whiskey A Go Go“, which inspired the name of a gene that causes the legs of anesthetized flies to shake similar to once-popular dance moves in said club. Fascinating.