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whymauri
1854 days ago
Did someone try editing out hERG?!
1 comments
ellimilial
1854 days ago
A fair amount of drugs inhibiting it had to be recalled after
https://pubmed.ncbi.nlm.nih.gov/16554806
and subsequent regulators actions.
link
whymauri
1854 days ago
Oh, OK -- right hERG inhibition liability is a candidate killer. It's just since the topic was gene editing, I thought someone had experimented with editing hERG somehow which had me really confused.
link