[mpettitt]

It's definitely on the label of my daily medication (in the UK), but it was interesting to see how the interaction seems to be fairly specific to grapefruit. Do either of the ancestor species have a similar effect?

I do wonder if there are other dietary/medication interactions that we simply haven't spotted, but which could allow for lower doses of medication (potentially with fewer side effects, if the effect was on one active component) or simply avoid some side effects altogether.

[thw0rted]

From the article:

> This interaction, by the way, seems to affect all of the bitter citruses—the ones that inherited the telltale tang from the pomelo. Sour orange. Lime, too. But it’s unlikely that anyone would drink enough sour orange or lime juice to have this effect, given how sour it is. Grapefruit, on the other hand, is far more palatable in large doses.

[hinkley]

I wonder what the concentrations are in bottled lime juice, which is easier to consume than fresh lime.