| The problem is a claim like the body/brain, the cells themselves needing to adapt to a new fuel source before seeing some benefits, taking months before you get there, actually contradicts the body's physiology. I don't really need to provide any citations, because the onus is on the one making those claims. And even if I provide citations, the goal posts will simply be moved, with lines like — the study was not long enough, the diet was not low carb enough, etc, etc. It also takes a lot of effort to dispel bullshit, much more effort than spreading it. Engaging with flat earthers is exhausting, most people don't do it due to insufficient knowledge and actual scientists don't engage b/c they've got better things to do. My language is emotionally charged because I've been in the keto community for a long time and I've witnessed a lot of quackery, which I believe can do harm to those in need, just like the anti-vaxers are doing. --- There are very few studies showing the effects of a ketogenic diet on cognition, in healthy subjects. Here's a study showing that a low-fat diet can have better psychological improvement, versus a low carb diet, even with similar weight loss:
https://jamanetwork.com/journals/jamainternalmedicine/articl... Here's a study that finds similar effects in mood between a low carb and a high carb diet, although the reaction time was improved in the low-fat group:
https://academic.oup.com/ajcn/article/86/3/580/4649430 Here's a study comparing cognitive performance between a high carb versus a log carb diet, showing similar results:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3789132/ Here's one study which merely says that people feel awful for the first two weeks and then start to feel less awful after reintroducing carbs — it's unfortunately not randomized:
https://naldc.nal.usda.gov/download/23706/PDF Here's a study that shows weight loss itself (the biggest confounder of every claim made by keto proponents) is known to affect mood and cognition and to improve quality of life:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905696/ Here's one paper arguing that most effects of drugs are attributable to placebo or nocebo:
https://www.annualreviews.org/doi/abs/10.1146/annurev-psych-... People on a diet also tend to do some exercise, here's one arguing about the positive effects of resistance training, which many in the keto community are engaging in:
https://jamanetwork.com/journals/jamapsychiatry/article-abst... --- Weight loss, exercise and placebo are actually the best explanations for most of the seemingly miraculous effects of the keto diet. --- Anyway, here's one for the depletion of glycogen:
https://science.sciencemag.org/content/254/5031/573.long Here's a graph showing roughly the evolution of glycogen and ketones during fasting, from "Harper's Biochemistry":
https://pbs.twimg.com/media/D-Q0MSPXUAEK_-r?format=jpg&name=... |
I do understand your goal post comment. It's super-frustrating that virtually all diet information out there has some tangential agenda (Eg. animal welfare, keto/paleo cultism, etc)