[Scoundreller]

> * Rate of conversion from on-label opioid prescription to addiction

And there we already have a problem. Off-label prescribing of opioids are a huge problem.

They’re really not supposed to be used so frequently for chronic non-cancer pain, but they’re used all the time for it.

And that’s a much bigger market than chronic cancer pain patients, because of life expectancy.

Cancer will often kill you, your back pain won’t.

[loeg]

Sorry, that wasn't really the idea I was trying to express at all. The two points are "using opioids as prescribed by Dr" => "using the same opioids in a way that was not prescribed."

I know off-label is specific industry jargon and it doesn't mean the way I tried to use it; sorry for the confusion.

Totally agree that chronic pain is a hard problem and tolerance effects make opioids a non-ideal long term solution. That said, I am neither a Doctor nor a researcher in the pharma industry so I don't have a lot of helpful suggestions for anything better than opioids today.