[Speculation] This is interesting to me because Crohn’s Disease (and Inflammatory Bowel Disease in general) is known to respond to certain antibiotics such as Metronidazole and Ciprofloxacin [1]. Maybe a analogous action is at play here.
Not sure if I understood correctly. Metronidazol helps to keep inflammation at bay ? Im asking because I was taking this antibiotic and Ive seen huge change in my skin inflammation, joint pains and bowel pains.
Fwiw: The article actually suggests that Psoriasis, (and IMHO, by extension, potentially autoimmune disease in general), are associated with liver dysfunction, driven by bowel disease.
The research and resulting protocol is inspired by an earlier Hungarian study in 2003 [1] that was able to seemingly cure psoriasis in 79% of its 500 test subjects. We don't know for sure; but 2 years later, 58% were still in complete remission. To be clear, that's a completely unheard-of result in psoriasis research.
All current, "mainstream" forms of treatment for psoriasis only treat the symptoms, not the cause. Even the newest, most advanced immune-suppressing biologics are merely stupid off buttons for the signaling misfiring that causes the superficial symptoms; meanwhile, psoriasis sufferers have much-higher-than-average incidences of cancer, liver disease, heart disease, IBD and so on. Treatments only keep the skin/joint symptoms at bay, and require the patient to continue taking the drugs, which tend to stop working after a while.
Pretty excited about this direction in psoriasis research.
Fwiw, I've found infrared induced hyperthermia to be extremely useful, but it's gruelling, time consuming and has a very short period of effect. I've been performing it most days for ~12 months.
"...nine cycles of whole-body hyperthermia (target body core temperature, 38.5 degrees C; duration, 50 min)... caused a significant reduction of all cytokines by 40-50%"