[atombender]

I've read that paper. It's fascinating.

The research and resulting protocol is inspired by an earlier Hungarian study in 2003 [1] that was able to seemingly cure psoriasis in 79% of its 500 test subjects. We don't know for sure; but 2 years later, 58% were still in complete remission. To be clear, that's a completely unheard-of result in psoriasis research.

All current, "mainstream" forms of treatment for psoriasis only treat the symptoms, not the cause. Even the newest, most advanced immune-suppressing biologics are merely stupid off buttons for the signaling misfiring that causes the superficial symptoms; meanwhile, psoriasis sufferers have much-higher-than-average incidences of cancer, liver disease, heart disease, IBD and so on. Treatments only keep the skin/joint symptoms at bay, and require the patient to continue taking the drugs, which tend to stop working after a while.

Pretty excited about this direction in psoriasis research.

[1] https://www.sciencedirect.com/science/article/pii/S092846800...

[WalterSear]

Fwiw, I've found infrared induced hyperthermia to be extremely useful, but it's gruelling, time consuming and has a very short period of effect. I've been performing it most days for ~12 months.

"...nine cycles of whole-body hyperthermia (target body core temperature, 38.5 degrees C; duration, 50 min)... caused a significant reduction of all cytokines by 40-50%"

https://www.ncbi.nlm.nih.gov/pubmed/19089489

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6263304/

I started the protocol outlined in Dr. Ely's paper recently. It seems to have reduced my symptoms somewhat, but it's too early to tell for sure.