[semenko]

Probably because most data disagree with this comment. There's a ~20% relative risk reduction in vascular events & mortality per ~40 mg/dL decrease in LDL.

The CTT is probably the best summary of these data: https://www.cttcollaboration.org/

[virtuallynathan]

> "~20% relative risk reduction in vascular events & mortality per ~40 mg/dL decrease in LDL."

Is that a composite endpoint of vascular events AND mortality?

From TheNNT:

"It takes 5 years of daily statin therapy to achieve a 1.6% chance of avoiding a heart attack, and a 0.37% chance of avoiding a stroke. Most disappointing, statins seem unable to prevent death in this group. And most concerning, the drugs may increase diabetes, a serious and life-altering disease." (Primary Prevention)

http://www.thennt.com/nnt/statins-for-heart-disease-preventi...

[village-idiot]

That would be the same CTT that makes money from the makers of Statins and has been accused of being insufficiently transparent around their studies[0].

0 http://www.drjohnm.org/2014/06/growing-doubt-on-statin-drugs...