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by virtuallynathan 2561 days ago
> "~20% relative risk reduction in vascular events & mortality per ~40 mg/dL decrease in LDL."

Is that a composite endpoint of vascular events AND mortality?

From TheNNT:

"It takes 5 years of daily statin therapy to achieve a 1.6% chance of avoiding a heart attack, and a 0.37% chance of avoiding a stroke. Most disappointing, statins seem unable to prevent death in this group. And most concerning, the drugs may increase diabetes, a serious and life-altering disease." (Primary Prevention)

http://www.thennt.com/nnt/statins-for-heart-disease-preventi...