[UltimateFloofy]

I am all for self-experimentation, however, when it exposes risk to humanity, I think we should tread carefully. In the long run, will these genes or other self-experiments be introduced into the global genome with unintended consequences?

[jerf]

The probability of that is basically the same as the probability of an already-existing known deleterious mutation being transmitted into the "global genome". Only if he has children in the future, and not necessarily even then.

Gene changes aren't intrinsically infectious; they're only infectious at all because we tend to modify infectious organisms to carry our changes (e.g., viral gene therapy).

[copperx]

I always dismissed Children of Men as laughably implausible. But with CRISPR it seems like it could happen at least to a portion of the population, given enough generations.

[notatcomputer68]

In the long term we should bee able to clean it up again. I'd be more worried about shorter terms