| Yes. For me the greatest remaining mysteries are more in this order. 1. Nature of Life (we are still nowhere near understanding how it arose or how living organisms work in all their intricate detail). 2. Nature of Consciousness - what is consciousness, how can living matter instantiate it, how can we quantify it, etc? 3. Origin of the Universe 4. Why do we seem so alone in the Universe? 5. Resolving Quantum Mechanics / Gravity 6. Understanding Time |