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by fundamental 2971 days ago
Thanks for writing this summary. Plenty of people get the wrong idea when it comes to test accuracy for topics like health diagnosis.

In the case of this particular topic it does seem like the outlined test could be another tool that doctors could utilize. If for instance a child has shown a change in developmental milestones then that observation comes with it's own (somewhat doctor specific) sensitivity and specificity. That information could be combined with the EEG test to improve the overall doctor+test accuracy. Nothing's going to be perfect, but the outlook is a bit more positive than presented in your example.

1 comments

>Nothing's going to be perfect, but the outlook is a bit more positive than presented in your example.

Ideally what would happen is that the doctor would use their judgement to narrow down the candidates who the test is applied to who have strong priors of Autism. That would substantively increase PPV. You'd need a ~50% prevalence before you get to 95% PPV