[yummyfajitas]

All you're saying is models are imperfect. That's true. That doesn't mean you need a standard deviation or more than 1 sample.

In this case, the model of 1/36 odds of rolling 2x6 would have to actually be 1/20 (or smaller) to invalidate this test. Do you find it plausible that the bias in 2 die is that high?

[Retric]

In that specific case yes, because there was no dice roll it was just a comic.

In a wider context that single data point is evidence that the detector was tripped or was not tripped. But, unlike a Bayesian the frequentest does not say they then know the actual probability involved and they don't update their priors. Because, to do it correctly you need to pick a P value and a model before doing the test.

Significant: https://xkcd.com/882/ makes a similar mistake by assuming a frequentist would accept that study design before running the tests. Multiple tests require more evidence, though when multiple groups are involved and not all publish you do get this problem.