[MichaelApproved]

If you have a middle mouse button, you can middle click a link to open it in a new tab. Of course, that's if you didn't reprogram the middle button to do something else.

[jevinskie]

Reprogramming the meat behind the keyboard is often harder than reprogramming the machine.

[douche]

With mice that don't have real middle buttons, trying to click the scroll-wheel without triggering a scroll event instead can be very trying...