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1.
CRISPR tech selectively shreds cancer cells, including "undruggable" cancers (innovativegenomics.org)
621 points by gmays 7 hours ago | 164 comments
2.
Swift at Apple: Migrating the TrueType hinting interpreter (swift.org)
88 points by DASD 3 hours ago | 36 comments
3.
How to setup a local coding agent on macOS (ikyle.me)
199 points by kkm 5 hours ago | 64 comments
4.
Renault: Electric motors with no rare earths (renaultgroup.com)
11 points by bestouff 56 minutes ago
5.
Malware developers added nuclear and biological weapons text to to their spyware (twitter.com)
251 points by marc__1 1 day ago | 171 comments
6.
Pirates, a naval warfare game inspired by Sid Meier's Pirates (piwodlaiwo.github.io)
163 points by iweczek 5 hours ago | 69 comments
7.
Congress just rushed through a disastrous copyright office overhaul (eff.org)
64 points by Cider9986 1 day ago | 4 comments
8.
Palantir loses legal challenge against Swiss investigative magazine (ft.com)
112 points by sschueller 2 hours ago | 20 comments
9.
Twenty One Zero-Days in FFmpeg (depthfirst.com)
10 points by redbell 50 minutes ago | 3 comments
10.
Launch HN: BitBoard (YC P25) – Analytics Workspace for Agents (bitboard.work)
30 points by arcb 6 hours ago | 17 comments
11.
Mmorpg World of ClaudeCraft, vibe coded with Fable 5 (worldofclaudecraft.com)
70 points by beatthatflight 2 hours ago | 61 comments
12.
Can I Buy Your KV Cache? (arxiv.org)
25 points by MediaSquirrel 2 hours ago | 20 comments
13.
Slightly reducing the sloppiness of AI generated front end (envs.net)
154 points by FergusArgyll 8 hours ago | 107 comments
14.
"Don't You Just Upload It to ChatGPT?" (correresmidestino.com)
244 points by speckx 5 hours ago | 210 comments
15.
Introduction to UEFI HTTP(s) Boot with QEMU/OVMF (blog.yadutaf.fr)
66 points by jtlebigot 8 hours ago | 25 comments
16.
EV demand up 50% in France and Germany since Iran war (reuters.com)
94 points by a_paddy 4 hours ago | 41 comments
17.
A PDF that changes based on how its read (sgaud.com)
111 points by SarthakGaud 6 hours ago | 57 comments
18.
Where Did Earth Get Its Oceans? Maybe It Made Them Itself (quantamagazine.org)
93 points by ibobev 7 hours ago | 56 comments
19.
Cosmodial Sky Atlas (killedbyapixel.github.io)
23 points by memalign 4 hours ago | 4 comments
20.
If you are asking for human attention, demonstrate human effort (tombedor.dev)
1474 points by jjfoooo4 1 day ago | 455 comments
21.
Maxproof (arxiv.org)
123 points by ilreb 11 hours ago | 10 comments
22.
Show HN: Turn your name into a tree in an infinite procedural shanshui landscape (landscape.bairui.dev)
6 points by subairui 2 days ago | 2 comments
23.
There Is Life Before Main in Rust (grack.com)
64 points by mmastrac 1 day ago | 17 comments
24.
Hazel (YC W24) Is Hiring a Full Stack Engineer (ycombinator.com)
1 points by augustschen 9 hours ago
25.
I Am Not a Reverse Centaur (blog.miguelgrinberg.com)
234 points by ibobev 5 hours ago | 168 comments
26.
Most Beautiful Will Ever Made (1936) (paperspast.natlib.govt.nz)
26 points by cf100clunk 4 hours ago | 12 comments
27.
/architect: Reduce Fable tokens by 80%, Fable orchestrates/reviews, Codex builds (github.com)
5 points by DanMcInerney 2 hours ago
28.
A dumpster arrived behind my university's library (yalereview.org)
146 points by mooreds 8 hours ago | 135 comments
29.
Show HN: StackScope – I crawled over 40k indie launches to see what they ship (stackscope.dev)
39 points by datafreak_ 7 hours ago | 12 comments
30.
WASI 0.3 (bytecodealliance.org)
224 points by mavdol04 9 hours ago | 86 comments