[longwave]

In some models, you can swap Ctrl and Fn in the BIOS. I find it much easier to hit a Ctrl-Shift combo with Ctrl on the far left.

[theintern]

I don't understand why they put the FN on the left. Maybe it's because Ctrl+Shift isn't that common a gesture for the general population, but switching them in the BIOS is the first thing I do.

[smhg]

In addition, also physically swap the buttons.

At least on my 5y old Thinkpad Edge 11 it was easy.

Use something like a credit card to remove the keys. And put them back with a firm press.

[longwave]

Unfortunately this isn't possible on newer keyboards, as Ctrl and Fn have different sized keycaps.