[baddox]

I have the same issue with screen sessions. I use Ctrl-a to move to the beginning of the line (an Emacs shortcut, also implemented in lots of shells), but screen's default command prefix is Ctrl-a. Of course, that one's simple to change.

[bm98]

Ctrl-a Ctrl-k in Emacs moves to the beginning of the line and then erases the line. In screen, that key combination kills the current window! At some point, screen added a "Really kill this window [y/n]" which was a terrific enhancement...

[baddox]

Ha, I don't remember running into that exactly. I have found several lines in my local text editor where I type "a" at the beginning because I mistakenly think I'm in screen, so I type "Ctrl-a a" instead of just "Ctrl-a".

[jweather]

Change screen's hotkey to something else. I like Ctrl-b.